Title: A Study of the Efficacy of Microneedling with Topical Autologous Platelet Rich Plasma in the Treatment of Acne Scars in a Tertiary Care Centre
Authors: Priyadharsini R, Kaviarasan PK, Prasad PVS, Kannambal K, Poorana B, Abhirami C
DOI: https://dx.doi.org/10.18535/jmscr/v7i10.27
Abstract
Background: Acne scars poses a significant psychosocial morbidity in this era of aesthetic concern. Acne scars can be classified into three types–atrophic, hypertrophic & keloidal. Atrophic acne scars are the most common type. Many treatments are available for treating post acne scars. Platelet–rich plasma (PRP) may be useful in atrophic scars by promoting collagen deposition. Microneedling also releases growth factors, which initiates a cascade of wound healing resulting in collagen deposition. Hence, microneedling and PRP should act synergistically to improve acne scars.
Objective: To assess the efficacy of microneedling with topical autologous platelet rich plasma in the treatment of acne scars.
Material and Methods: The study enrolled 20 cases of acne scars. Microneedling with topical PRP was applied over acne scars. They received 4 sequential treatments with an interval of 4 weeks between each session. At first visit, scars were graded according to Goodman and Baron’s qualitative acne scar grading system. After 4 sessions objective assessment of physician scores of improvement were determined by Goodman and Baron’s qualitative &quantitative acne scar grading system.
Results: Male female ratio was 0.43:1. After completion of 4 sessions, qualitative assessment revealed reduction by 3 grades in 12 patients (60%) and Quantitative assessment showed 8 patients (40%) with very good reduction. Photographs were taken at each visit and compared.
Conclusion: Microneedling with topical PRP was safe, superior and efficacious in treating acne scars.
Keywords: Acne scars, Platelet Rich Plasma, microneedling, Goodman and Baron’s qualitative and quantitative acne scar grading system.
