Abstract
Background: Renal cancer is among the top ten causes of death due to cancer world-wide in both, men and women. Surgical resection is the mainstay of treatment. However, Histopathological examination is the gold standard of diagnosis. It is imperative to study the types and subtypes of renal cancer leading to nephrectomy.
Method: A hospital-based cross-sectional study, observing demographic profile and clinical details of histopathological examination
Results: This study included 28 patients with age range from 1 year to 75 years. The peak age of incidence was the 4th decade. Incidence in males and females was equal. The maximum number of cases (50%) were diagnosed as renal cell carcinoma. Other histopathological diagnoses found were Wilms tumour, oncocytoma, cystic nephroma, and angiomyolipoma. Among Renal cell carcinomas (50%), the Clear cell variant was the most common, whereas Wilm’s tumor was the most common in the pediatric age group.
Conclusion: Regional study for types of renal cancer in a diverse geographical country like india helps plan diagnostic and treatment modalities with optimum allotment of resources.
Keywords: renal cancer, renal cell carcinoma, wilms tumor, nephrectomy.
References
- Mahdavifar N, Mohammadian M, Ghoncheh M, Salehiniya H. Incidence, Mortality and Risk Factors of Kidney Cancer in the World.
- BlueBooksOnline [Internet]. [cited 2024 Aug 29]. Available from: https://tumourclassification.iarc.who.int/chaptercontent/36/4
- Kunath F, Schmidt S, Krabbe L, Miernik A, Dahm P, Cleves A, et al. Partial nephrectomy versus radical nephrectomy for clinical localised renal masses. Cochrane Database Syst Rev. 2017 May 9;2017(5):CD012045.
- Goyal S, Shah N. Histopathological study of nephrectomy specimens in a tertiary care hospital. IP J Diagn Pathol Oncol. 2019 Mar 28;4(1):39–44.
- Basnet D, Makaju R, Dhakal R, Lama B, Gautam N. Histomorphological Spectrum of Lesions in Nephrectomy Specimen. J Coll Med Sci-Nepal. 2021 Jun 30;17(2):93–100.
- Thakur AS, Gahine R, Banjare B. A Histopathological spectrum of nephrectomy specimens in a tertiary hospital of Raipur city (C.G.) India. Trop J Pathol Microbiol. 2019 Sep 30;5(9):627–32.
- Krishna M. Histopathological Spectrum of Lesions in Nephrectomy Specimens in a Tertiary Care Hospital. Indian J Pathol Res Pract. 2020 May 1;9(2 (Part-I)):41–8.
- Abbas F, Aalmeen G, Latief M, Wani S, Wani M, Farooq S. Histopathological Spectrum of Nephrectomies; a Single Centre Experience of over 14 Years. J Ren Hepatic Disord. 2022 Apr 13;6(1):36–40.
- Sheenu VS, Paul RS, Pushpa M, Ami EM, Rashmi R, Iona ML, et al. Histopathological spectrum of adult renal tumours: A single center experience and review of literature. Indian J Pathol Microbiol. 2023 Jun;66(2):307.
- Chandanwale SS, Naragude P, Singh M, Charusheela G, Desai A, Sadbhawana. Spectrum of pathological lesions in nephrectomy specimens: A study of 50 lesions. IP J Diagn Pathol Oncol. 4(4):292–8.
- Ghalayini IF. Pathological Spectrum of Nephrectomies in a General Hospital. Asian J Surg. 2002 Apr 1;25(2):163–9.
Corresponding Author
Dr Priyanka Baishya
Department of Pathology, Gauhati Medical College, Assam, India