Title: Incidence of Use of Contraindicated Oral Hypoglycemic Drugs in New Patients of Diabetic Nephropathy Visiting OPD of Tertiary Care Hospital
Author: Dr Vikrant Kumar, Dr MD Faiyaz Alam, Dr P.K. Agrawal
DOI: https://dx.doi.org/10.18535/jmscr/v9i10.25
Abstract
Introduction
Diabetes is one of the leading causes of chronic renal disease and end stage renal disease1. Chronic renal disease is associated with decreased clearance of many oral hypoglycaemic agents (OHAs) and their metabolites, prolonging the duration of exposure to the drug and its metabolites, more so in patients with moderate to severe renal disease2. Thus, a diagnosis of renal disease in patients with diabetes merits attention to the revision of the drug therapy of the patient. But, managing hyperglycemia in CKD patients is difficult, partly due to the complexity involved in these patients, and partly due to less data supporting benefits of strict glycemic control3. Inspite of this, there is major use of contraindicated oral hypoglycaemic agents in diabetic nephropathy.
Aims and Objective
In this study, we are focusing on studying the incidence of use of non-recommended Oral Hypoglycaemic drugs in new patients of diabetic nephropathy visiting opd of tertiary care hospital.
Materials and Methods
A total 600 already diagnosed patients of diabetic nephropathy who visited OPD were recruited in this retrospective, cross-sectional study and were evaluated for use of OHAs according to their medical prescription.
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