Title: Predictors of Cognitive Impairment in Stroke Servivors
Authors: Gharib F. Mohamed, HemedM. Baddary, Mohamed N. Thabit, A. Ammar Ghaibeh, Alaaeldin Sedky Bakhit Farrag, Ahmad G. Arafa
DOI: http://dx.doi.org/10.18535/jmscr/v4i8.14
Abstract
References
The aim of this study is to determine the various risk factors and stroke characteristics that play a role in development of poststrokecongnitive impairment. A total of 119 chronic stroke patients were included in the study. Patients with history of psychiatric, medical or taking drugs that cause cognitive impairement were excluded from the study. The stroke patients were classified into normal or having mild, moderate and severe congnitiveimpairement according to the mini-mental state examination. Demographic variables and stroke risk factors including; age, sex, hypertension, diabetes mellitus, smoking, cardiac diseases, prior history of stroke or transient ischemic attacks were assessed. Various stroke symptomatology, history of delirium with the onset of stroke, and history of poststroke epilepsy were assessed.Barthel index and Beck depression scale were used to assess the global poststroke disability and poststroke depression. The lesion type, site, side, and size were assessed from the relevant brain imaging. The role of various previously mentioned factors in development of poststroke cognitive impairement were tested using the appropriate statistical test and C 4.5 decision tree for those factors were done.elderly stroke patients with multiple large sized strokes especially in the left hemisphere, those with cortical lesion, those associated with delirious onset, those who develop poststroke epilepsy and/or depression, and finally those patients with severe poststrokediseability are more likely to suffer psotstroke cognitive impairement.Early cognitive rehabilition methods and medical treatment with antidementia medications should be provided for patients with the associated previously mentioned factors.
Keywords: Stroke, Cognitive, Dementia, Predictors.
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