Title: Pancreatic Tuberculosis: An Unusual Cause for Pancreatic Mass Mimicking Malignancy
Authors: Dr. Akhila Jose, Dr. P Ravi, Dr. Divyasri
DOI: https://dx.doi.org/10.18535/jmscr/v13i09.04
Abstract
Introduction
Pancreatic tuberculosis is very rare even in regions with high prevalence of tuberculosis, with an incidence reported to be less than 4.7 %. Tuberculosis of the pancreas is extremely rare and in most of the cases mimics pancreatic carcinoma. Patients of pancreatic tuberculosis may remain asymptomatic initially and manifest as an abscess or a mass involving local lymph nodes and usually present with non-specific features.
Case Report
76-year-old male patient, labourer by occupation who is a resident of Mehabubabad was referred from General Surgery Department for tuberculosis work up. The patient presented with one month history of upper abdominal pain, fever with evening rise of temperature, loss of appetite and loss of weight. No history of vomiting, loose stools, cough, shortness of breath, chest pain. He is a known case of systemic hypertension and Hypothyroid in the past six years. Also, a known case of coronary artery disease undergone coronary bypass graft three years back. He is a chronic smoker and alcoholic. Inspite of symptomatic treatment patient had no relief. Vitals were stable. On abdomen examination tenderness was present in epigastric and right hypochondriac region. No palpable mass present. Routine Blood investigations were within normal limits. Chest x-ray was normal. On Sputum CBNAAT was not detected. USG Abdomen and KUB report suggested well defined conglomerate heterogeneously hypoechoic lesion in peripancreatic body. Heterogeneously enhanced mass lesion 7*6*5 cm arising from body of pancreas with peripancreatic lymphnodes suggestive of malignancy was noted in CECT Abdomen. Gastroenterology and Surgical Oncology referral was done. Upper GI Endoscopy suggestive of GE junction obstruction. Malignancy was suspected; CA 19-9 was 8IU/L. Surgical Laparotomy was done and sample tissue was sent for histopathological examination (HPE). HPE report came to ne necrotising granulomatous inflammation possibly Mycobacterial in origin and biopsy tissue CBNAAT was MTB detected Rifampicin sensitive hence diagnosed as Pancreatic Tuberculosis. Patient was started on ATT and advised follow up.
References
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- Nayak, Hemanta Kumar; Patra, Susama1; Rai, Abhijeet; Makashir, Madhav Sameer; Panigrahi, Chinmayee1; Chaudhary, Mansi; Tripathy, Taraprasad2; Mishra, Pritinanda1; Pattnaik, Bramhadatta3; Panigrahi, Manas Kumar; Samal, Subash Chandra. Pancreatic Tuberculosis. Gastroenterology, Hepatology and Endoscopy Practice 3(3):p 76-81, Jul–Sep 2023. | DOI: 10.4103/ghep.ghep_3_23
- Shaikh OH, Sunil J, Prakash S, Vijaykumar C, Kumbhar US. Isolated pancreatic tuberculosis masquerading pancreatic malignancy. BMJ Case Rep. 2023 Jul 4;16(7):e254250. doi: 10.1136/bcr-2022-254250. PMID: 37402588; PMCID: PMC10335409.
