Title: Polycystic Ovary Syndrome in Light of Hormonal Panel Interpretations Literature Review

Authors: Dr Teeba Salwan Kamal Abbood, Dr Rand Salwan Kamal Abbood

 DOI: https://dx.doi.org/10.18535/jmscr/v13i08.08

Abstract

 

Polycystic ovary syndrome (PCOS) is a common endocrine-metabolic disorder defined by a triad of ovulatory dysfunction, hyperandrogenism, and polycystic ovarian morphology (PCOM).

The "hormonal panel" for PCOS includes ovarian and adrenal androgens, gonadotropins, sex hormone–binding globulin (SHBG), anti–Müllerian hormone (AMH), and tests that rule out other conditions (like TSH, prolactin, and 17-hydroxyprogesterone).

In the last ten years, evidence-based guidelines have improved diagnostic and management pathways and have thought about how to interpret certain analytes, especially AMH.

This review consolidates contemporary evidence regarding the diagnostic, phenotyping, and prognostic functions of the hormonal panel in PCOS, emphasizing the advantages and drawbacks of essential biomarkers and presenting practical testing algorithms derived from the 2023 International Evidence-based PCOS Guideline and recent systematic reviews.

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