Title: Stability Analysis of Pharmaceutical Preparations under Different Storage Conditions

Authors: Abdulrahman Hamoud Alanazi, Meshal Bakheet Alotaibi, Mohammed Saud Alharbi, Abdulkarim Abdulrahman, Abdulrahman Abdulkarim Alanazi

 DOI: https://dx.doi.org/10.18535/jmscr/v12i09.03

Abstract

The stability of pharmaceutical preparations is a critical factor affecting their efficacy, safety, and shelf life. Variations in storage conditions, including temperature, humidity, and light exposure, can significantly influence the physical and chemical properties of these preparations. This paper investigates the stability of pharmaceutical preparations under varying storage conditions, focusing on the degradation rate of active ingredients, physical changes, and the impact of packaging materials. Data collected from accelerated and long-term stability studies are analyzed to provide recommendations for optimal storage conditions.

Keywords: Pharmaceutical stability, degradation, storage conditions, accelerated stability testing, temperature, humidity, light exposure, active pharmaceutical ingredients (API), tablets, solutions, suspensions, packaging materials, shelf life, refrigeration, photodegradation.

References

  1. International Council for Harmonisation (ICH) Q1A(R2), *Stability Testing of New Drug Substances and Products*.
  2. Waterman KC, et al., “Stability analysis of pharmaceutical formulations: Impact of temperature and humidity,” *Journal of Pharmaceutical Sciences*, 2014.
  3. Moreton RC, “Stability of dosage forms and the influence of packaging,” *Pharmaceutical Technology*, 2017.

Corresponding Author

Abdulrahman Hamoud Alanazi