In India, febrile illness is one of the most common reasons for seeking medical attention, but there is limited information on the frequency of specific infections.

Aim: To evaluate the causes of fever in patients.

Method: 300 patients presented with fever seen between October 2019 to march 2020 were included in study.

Results: In our study most common disease associated with fever was upper respiratory tract infection; 28.8% male and 26.8% female were diagnosed with URTI respectively. Second most common disease associated with fever was enteric fever; 20.3% male and 15.4% female were diagnosed with enteric fever. Dengue fever was the third most common disease associated with fever in our study; 16,3% male and 13% female had dengue fever. Urinary tract infection (UTI) and malaria were the fourth and fifth most common disease found in our study.

Conclusion: Among febrile illness, URTI, enteric fever, dengue fever and malaria were the most common in this study. Scrub typhus should be considered in the differential diagnosis of patients with acute febrile illness.  Tuberculosis needs to be considered in the diagnosis of  febrile illnesses

Keywords: Febrile illness, Upper respiratory tract infection, Enteric fever, Malaria, Dengue fever, Scrub typhus.

1. WHO: The 10 leading causes of death by broad income group ( 2008).2011
2. Archibald L K, Reller L B, 2001. Clinical microbiology in developing countries. Emerg Infect dis 7: 302-305.
3. Sood S, Kapil A, Dash N, Das B K, Goel V, Seth P, 1999. Paratyphoid fever in India: an emerging problem. Emerg Infect Dis 5: 483-484.
4. Chandel DS, Nisar N, Thong KL, Pang T, Chaudhary R, 2000.Role of molecular typing in an outbreak of salmonella paratyphi A. Trop Gastroenterol 21: 121-123
5. David R Murdoch et.alTheetiology of febrile illness in adults presenting to Patan hospital in Kathmandu, Nepal.Am.J,Trop Med 6,2004: 670-675.
6. Chaturvedi HK, Mahanta J, Pandey A. Treatment- seeking for febrile illness in north- east India: an epidemiological study in malaria endemic zone. Malar J.2009,8(1):301-310.
7. Chandramohan D, Jaffar S, Greenwood B: use of clinical algorithms for diagnosing malaria. Trop Med Int Health. 2002,7(1):45-52.
8. Mwangi T W, Mohammed M et al. Clinical algorithms for malaria diagnosis lack utility among people of different age groups. Trop Med Int Health. 2005;10(6):530-536.
9. Rajnish Joshi, John M colford Jr, Arthur L. Reingold, Shriprakash Kalantri. Non malarial acute undifferentiated fever in a rural hospital in central india. Am J Trop Med 78(3), 2018: 393-399.
10. Vinetz JM, 2003. Detection of leptospirosisin India. Arch Dis Child 88:1033.
11. Lal M, Aggarwal A, Oberoi A, 2007. Seroprevalance of leptospirosis In patients of PUO in Ludhiana. Indian J Pathol Microbiol 50:78-79.
12. Soo-yoon Moon, Ki-Ho Park, Mi Suk Lee, Jun Seong Son, Hospital-acquired fever in oriental medical hospitals, BMC Health Services Rearch (2018) 18:88, https://doi.org/10.1186/s12913-018-2896-1(accessed on 15/04/21)
13. James et al, Etiology and Resource Use of Fever Of Unknown Origin in Hospitalised Children, Hospital paediatrics, 8(3): 2018; 135-141.
14. Mariraj I, Mohammad Adil et al. A study on clinical profile of acute undifferentiated febrile illness in a tertiary care hospital. International J of Adv in Med.2020; 7(3):404-407.
15. Singh R, Singh SP, Ahmad N. A study of etiological pattern in an epidemic of acute febrile illness during monsoon in a tertiary health care institute of Uttarakhand, India. J Clin Diag Res. 2014 Jun;8(6):MC01.

Dr Govind Kumar

Additional Professor, Deptt of General Medicine, IGIMS, Sheikhpura, Patna, Bihar, India