Title: HbA1C Levels and its correlation in Diabetic Retinopathy
Authors: Dr Saba Eqbal, Dr Atul Mishra, Dr Danish Halim, Dr Aftab
DOI: https://dx.doi.org/10.18535/jmscr/v8i9.34
Abstract
The study aimed to determine the correlation of HbA1C with different grades of Diabetic Retinopathy.
80 participants were included in the study, in whom relevant history regarding their diabetes was noted i.e age at diagnosis of diabetes, duration of the diabetes, nature and duration of treatment received, glycemic control and compliance to the treatment. Patients were evaluated for their HbA1C levels, hypertension, lipid profile and renal parameters.
Each participant’s diabetic retinopathy status was classified according to the ETDRS system.
Our study found a correlation between different grades of diabetic retinopathy and CSME with HbA1C levels. The other factor which had a significant correlation was duration of diabetes.
Age of the patient, gender of the patient, hypertension, hyperlipidemia, modality of treatment and nephropathy did not have a significant correlation when compared in different grades of diabetic retinopathy.
References
- National society to prevent blindness. In: Visual problems in the US data analysis definition, data sources, detailed data tables, analysis, interpretation. New York: National society to prevent blindness; 1980;1-46.
- Aiello LP ,Gardner TW, King GL, Blankenship G, Cavallerano JD, Ferris FL 3rd, et al. Diabetic retinopathy. Diabetes Care 1998; 21 : 143-56).
- Sicree R, Shaw J, Zimmet P. Diabetes and impaired glucose tolerance. In: Gan D, editor. Diabetes Atlas. International Diabetes Federation. 3rd ed., Belgium: International Diabetes Federation; 2006. p.15–103.
- Wild S, Roglic G, Green A, Sicree R, King H. Global prevalence ofdiabetes, estimates for the year 2000 and projections for 2030.Diabetes Care. 2004;27:1047– 1053.
- Ronald J. Koenig, B.S., Charles M. et al Correlation of Glucose Regulation and Hemoglobin AIcinDiabetes Mellitus N Engl J Med 1976; 295:417-420
- American diabetes association “Tests of glycemia in diabetes”, Clinical practice recommendations. 2003.107-108
- Early Treatment of Diabetic Retinopathy Study Research Group. Grading diabetic retinopathy from stereoscopic color fundus photographs :an extension of the modified Airlie House Classification. ETDRS report number 10. Ophthalmology. 1991;98:786-806.
- Tapp RJ, Shaw JE, Harper CA, Balkau B, McCarty DJ, Taylor HR, Welborn TA, Zimmet PZ, The prevalence of and Factors Associated with diabetic retinopathy in the Australian Population, Diabetes Care 2003; 26:1731-7.
- Santos KG, Tschiedel JR, Schneider KEP, Roisenberg I, Prevalence of retinopathy in Caucasian type 2 diabetic patients from South of Brazil and relationship with clinical and metabolic factors. Braz J Med Biol Res 2005; 38:221-5.
- Aiello LM, Rand LI, Briones JC, Wafai MZ, Sebestyen JG. Diabetic retinopathy in Joslin Clinic patients with adultonset diabetes. Ophthalmology 1981; 88 :619-23
- Aiello LM, Rand LI, Briones JC, Wafai MZ, Sebestyen JG. Diabetic retinopathy in Joslin Clinic patients with adultonset diabetes. Ophthalmology 1981; 88 :619-23
- Klein BEK, Klein R. Diabetic Eye disease. Lancet 1997; 350:197-204.