Title: An Observational Study on Effect of Dengue Fever on Liver Function in Patients Admitted to a Tertiary Care Centre in Rural South Kerala

Authors: Dr H Poornima, Dr Giri Vishnu

 DOI: https://dx.doi.org/10.18535/jmscr/v7i12.42

Background

Dengue is an important mosquito borne disease in the tropical and subtropical countries. It is often self limited and presents with arthralgia, myalgia, head ache and fever. Though not a hepatotropic virus, liver injury is not un common in dengue infection(1). The degree of liver dysfunction varies from mild to severe.(2,3) The exact mechanism of the liver dysfunction is not known, but is postulated to be either a direct effect of the virus or a dysregulated host immune response(2).  

The present study aims at finding the effects of dengue virus on the liver function and its effect on the severity and outcome of the disease in patients admitted in a tertiary care centre in south Kerala.

Aims and Objectives

  1. To study the pattern of liver function abnormalities in patients admitted with dengue.
  2. To study the effects of liver function abnormality on the severity and the outcome of dengue.

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