Introduction

Brunner gland adenoma is a rare tumour of the duodenum and presented as obstructive symptoms related to size of the lesions.

Clinical Picture

32 years old female presented to gastroenterology department for pain abdomen and not relieved by medications.

Investigations

Upper GI endoscopy performed. There was a huge polyp >5 cm seen in the duodenum I part. Mild erosions were noted on the surface.

Complete Hemogram - normal picture.

Patient was subjected to surgery and polyp was sent for histopathologic examination.

Macroscopic Findings

Received a polyp measuring 5 cm in size sent in 10 % formalin, processed and sections were subjected for microscopic examination.

Microscopic Findings

Sections studied shows a polypoidal duodenal mucosa with mild erosion, minimal inflammation of lamina propria. The submucosal florid proliferation of Brunner glands arranged in lobules of varying sizes and numbers. The lobules extended to lamina propria separated by delicate fibrous septae, few cystically dilated glands with basal position of nuclei. No mitotic activity.

Diagnosis

Microscopic picture is that of Brunner gland adenoma.

1. Surgical pathology of GI tract, liver, biliary tract and pancreas, second edition. Robert, D.ODZE, John.R.GOLD BLUM. PAGE NO. 448, 449
2. Gastrointestinal Pathology, Atlas Text 3^rd Edition Petu. G. Isaacson, Cecilia. M. Fenoglio. Preiser Page No. 472, 473
3. Surgical Pathology by Rosai & Ackerman’s 10^th Vo. I. Page No. 686, 687.

Dr Ezhilvizhi Alavandar