In Type 2 Diabetes Mellitus (T2DM) loss of minerals may lead to decrease in its bodily content and might affect the concentrations of minerals. The aims of this study were to compare the plasma glucose, glycated hemoglobin (HbA1c), and Magnesium (Mg) concentrations of patients with T2DM and healthy controls (Non-diabetic) in Bundelkhand region and also to know the association of blood glucose and HbA1c with Mg in respective groups. This study has shown altered Fasting Blood Sugar (FBS), HbA1c, and Mg in T2DM group subjects when compared with healthy control group subjects.  The statistical significance was observed to be at p<0.05. Insignificant difference was observed in the age parameter when compared between the two groups. In the present study pertaining to T2DM group subjects, an inverse correlation between Age and FBS; Age and HbA1c were established. In conclusion, we observed lower Mg levels in T2DM individuals in the Bundelkhand region. As Mg depletion aggravates insulin resistance and may result in increased loss through urine, therefore, it may be advisable to periodically monitor Mg concentrations in T2DM subjects. Moreover, further research is imminent to understand the deeper insights into the association of Mg with T2DM which is, prior to the initiation or after initiation of T2DM.

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Dr Prabhaksr Singh Bais

Assistant Professor, Head of the Dept., Biochemistry Department, MLB Medical College, Jhansi, India