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Abstract
Polyhydroxybutyrates (PHB) are bio-plastics that are produced by many microbial species under carbon rich and nutrient starvation conditions. Poly (ß-hydroxybutyrate) (PHB) belongs to a family of microbial energy/carbon storage compounds collectively known as poly hydroxyalkanoates. The organisms producing PHBs have been isolated, identified and the conditions of maximum production optimized. The cheaper raw material for the mass production of PHB are constantly being studied and suggested to lower the production cost. Most of the commercial productions are at present more expensive than synthetic polymer production. Since biopolymers offer the dual advantage of being formed from renewable resources and in addition to it they are also completely biodegradable, the structure, properties and regulation of synthesis and degradation of PHB should be reviewed and the microbial production of copolymers of 3-hydroxybutyrate and 3-hydroxyvalerate, with properties varying according to copolymer composition, must be considered.
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How to Cite
Rathore, P. S. (2014). Bioprospects of PHB: A Review. International Journal of Emerging Trends in Science and Technology, 1(04). Retrieved from https://igmpublication.org/ijetst.in/index.php/ijetst/article/view/141
References
1. Anderson, A., Haywood, G., & Dawes, E. Biosynthesis and composition of bacterial poly(hydroxyalkanoates). International Journal of Biological Macromolecules,12(1990).Butterworth & Co. Ltd.
2. Bitar, A. and Underhill, S. Effect of ammonium supplementation on production of Poly –β- hydroxybutyric acid by Alcaligenes eutrophus in batch culture. Biotechnol. Lett., 12(1990),563-568.
3. Arun, A.; Murrugappan, R.; Ravindran, A.D.D.; Veeramanikandan, V. and Balaji, S. Utilization of various industrial wastes for the production of poly-beta-hydroxy butyrate (PHB) by Alcaligenes eutrophus. Afr. J. Biotechnol., 5 (2006),1524-1527.
4. Lemoigne, M. gtudes sur I’autolyse microbienne. Acidification par formation d’acide P-oxybutyrique. Ann. Inst. Pasteur, 39(1925), l44.
5. Dawes, E. A. and Senior, P. J. Adv. Microbial Physiol. 10 (1973):135-266.
6. Aysel, U.; Sahin, N. and Beyatli, Y. Accumulation of Poly-β-Hydroxybutyrate in Streptomyces Species during Growth with Different Nitrogen Sources. Turk. J. Biol., 26 (2002), 171-174.
7. Comeau, Y., Hall, K.J., Oldham, W.K. Determination of Poly-Beta-Hydroxybutyrate and Poly-Beta Hydroxyvalerate in Activated-Sludge by Gas-Liquid-Chromatography. Appl. Environ. Microbiol. 54(9) (1988), 2325--2327.
8. Raveendran Sindhu , Balakrishnan Ammu, Parameswaran Binod , Sreelatha K. Deepthi, K. B. Ramachandran, Carlos Ricardo Soccol and Ashok Pandey. Production and Characterization of Poly-3-hydroxybutyrate from Crude Glycerol by Bacillus sphaericus NII 0838 and Improving Its Thermal Properties by Blending with Other Polymers Vol.54, n. 4(2011), pp. 783-794.
9. Lemos, P.C., Viana, C., Salgueiro, E.N., Ramos, A.M., Crespo, J.P.S.G. and Reiszcorr, M.A.M. Effect of carbon source on the formation of polyhydroxyalkanoates (PHA) by a phosphate-accumulating mixed culture. Enzyme and Microbial Technology. 22(8)(1998), 662-671.
10. Kaneka. Full-scale Development of the World's First Completely Bio-based Polymer with Soft and Heat-Resistant Properties. Kaneka corporation (2009).
11. Kosior, E. Lightweight Compostable Packaging: Literature Review. The Waste & Resources Action Programme (2006).
12. Lee, J., Lim, H., & Hong, J. Application of nonsingular transformation to on-line optimal control of poly-_-hydroxybutyrate fermentation. Journal of Biotechnology, 55(1997), 135- 150.
13. Patnaik, P. "Intelligent" descriptions of microbial kinetics in finitely dispersed bioreactors: neural and cybernetic models for PHB biosynthesis by Ralstonia eutropha. Microbial Cell Factories, 6 (2007), 23.
14. B.Senthil Kumar and G.Prabakaran ,Production of PHB (bioplastics) using bio-effluent as substrate by Alcaligens eutrophus,Indian Journal of Biotechnology, Volume5, (2006) pp 76-79.
15. Kitamara S, Doi Y. Staining method of poly (3- alkanoic acid) producing bacteria by Nile blue. Biotechnological Techniques 8(2004), 345-350.
16. Lee, S.. Review Bacterial Polyhydroxyalkanoates. Biotechnology and Bioengineering, 49 (1996b), 1-14. John Wiley & Sons, Inc.
17. Laurens Goormachtigh, Transcript of Modelling and simulation of heterotrophic PHB production. Modelling and simulation of heterotrophic PHB Production, (2013).
18. Edwin A. Dawes. Polyhydroxybutyrate: An Intriguing Biopolymer, Bioscience reports Vol.8(1988), No.6.
19. Page, W. & Knosp,O. Hyperproduction of poly-β-hydroxybutyrate druing exponential growth of Azotobacter vinelandii UWD. Applied and Environmental Microbiology, 55,(1989).1334-1339.
20. Suzuki, T., Yamane, T., & Shimizu, S. Mass production of poly-beta-hydroxybutyric acid by fed-batch culture with controlled carbon/nitrogen feeding. Applied Microbiology and Biotechnology, 24 (1986), 370-374.
21. Adwitiya Pal, Ashwini Prabhu,Avinash Arun Kumar,Badri Rajagopal, Kajal Dadhe,Vomsi Ponnamma, Srividya Shivakumar, Optimization of process parameter for maximum poly-β-hydroxybutyrate (PHB) production by Bacillus thuringiensis IAM 12077,Polish Journal of Microbiology, Vol.58(2) (2009), 149-154.
22. Dieter Jendrossek and René Handrick, Microbial degradation of Polyhydroxyalkanoates. Annual Review of Microbiology Vol. 56 (2002), 403-432.
23. Venkateswar Reddy, M., and Venkata Mohan, S. Influence of aerobic and anoxic microenvironments on polyhydroxyalkanoates (PHA) production from food waste and acidogenic effluents using aerobic consortia. Bioresource Technology. 103(1) (2012), 313-321.
24. Coats, E.R., VandeVoort, K.E., Darby, J. and Loge F.J. Toward polyhydroxyalkanoate production concurrent with municipal wastewater treatment in a sequencing batch reactor system. Journal of Environmental Engineering. 137(1) (2011), 46-54.
25. Choi, J. & Lee, S. Process analysis and economic evaluation for Poly(3-hydroxybutyrate) production by fermentation. Bioprocess Engineering, 17(1997), 335-342. Springer Verlag.
26. Sindhu, Raveendran et al. Production and Characterization of Poly-3-hydroxybutyrate from Crude Glycerol by Bacillus sphaericus NII 0838 and Improving Its Thermal Properties by Blending with Other Polymers, Arch. Biol. Technol. v.54 n.4: pp. 783-794, July/Aug 2011).
27. N.Phanse et al., Screening of PHA (poly hydroxyalkanoate) producing bacteria from diverse sources, International Journal of Biosciences (IJB) Vol. 1, No. 6, p. 27-32, 2011 .
2. Bitar, A. and Underhill, S. Effect of ammonium supplementation on production of Poly –β- hydroxybutyric acid by Alcaligenes eutrophus in batch culture. Biotechnol. Lett., 12(1990),563-568.
3. Arun, A.; Murrugappan, R.; Ravindran, A.D.D.; Veeramanikandan, V. and Balaji, S. Utilization of various industrial wastes for the production of poly-beta-hydroxy butyrate (PHB) by Alcaligenes eutrophus. Afr. J. Biotechnol., 5 (2006),1524-1527.
4. Lemoigne, M. gtudes sur I’autolyse microbienne. Acidification par formation d’acide P-oxybutyrique. Ann. Inst. Pasteur, 39(1925), l44.
5. Dawes, E. A. and Senior, P. J. Adv. Microbial Physiol. 10 (1973):135-266.
6. Aysel, U.; Sahin, N. and Beyatli, Y. Accumulation of Poly-β-Hydroxybutyrate in Streptomyces Species during Growth with Different Nitrogen Sources. Turk. J. Biol., 26 (2002), 171-174.
7. Comeau, Y., Hall, K.J., Oldham, W.K. Determination of Poly-Beta-Hydroxybutyrate and Poly-Beta Hydroxyvalerate in Activated-Sludge by Gas-Liquid-Chromatography. Appl. Environ. Microbiol. 54(9) (1988), 2325--2327.
8. Raveendran Sindhu , Balakrishnan Ammu, Parameswaran Binod , Sreelatha K. Deepthi, K. B. Ramachandran, Carlos Ricardo Soccol and Ashok Pandey. Production and Characterization of Poly-3-hydroxybutyrate from Crude Glycerol by Bacillus sphaericus NII 0838 and Improving Its Thermal Properties by Blending with Other Polymers Vol.54, n. 4(2011), pp. 783-794.
9. Lemos, P.C., Viana, C., Salgueiro, E.N., Ramos, A.M., Crespo, J.P.S.G. and Reiszcorr, M.A.M. Effect of carbon source on the formation of polyhydroxyalkanoates (PHA) by a phosphate-accumulating mixed culture. Enzyme and Microbial Technology. 22(8)(1998), 662-671.
10. Kaneka. Full-scale Development of the World's First Completely Bio-based Polymer with Soft and Heat-Resistant Properties. Kaneka corporation (2009).
11. Kosior, E. Lightweight Compostable Packaging: Literature Review. The Waste & Resources Action Programme (2006).
12. Lee, J., Lim, H., & Hong, J. Application of nonsingular transformation to on-line optimal control of poly-_-hydroxybutyrate fermentation. Journal of Biotechnology, 55(1997), 135- 150.
13. Patnaik, P. "Intelligent" descriptions of microbial kinetics in finitely dispersed bioreactors: neural and cybernetic models for PHB biosynthesis by Ralstonia eutropha. Microbial Cell Factories, 6 (2007), 23.
14. B.Senthil Kumar and G.Prabakaran ,Production of PHB (bioplastics) using bio-effluent as substrate by Alcaligens eutrophus,Indian Journal of Biotechnology, Volume5, (2006) pp 76-79.
15. Kitamara S, Doi Y. Staining method of poly (3- alkanoic acid) producing bacteria by Nile blue. Biotechnological Techniques 8(2004), 345-350.
16. Lee, S.. Review Bacterial Polyhydroxyalkanoates. Biotechnology and Bioengineering, 49 (1996b), 1-14. John Wiley & Sons, Inc.
17. Laurens Goormachtigh, Transcript of Modelling and simulation of heterotrophic PHB production. Modelling and simulation of heterotrophic PHB Production, (2013).
18. Edwin A. Dawes. Polyhydroxybutyrate: An Intriguing Biopolymer, Bioscience reports Vol.8(1988), No.6.
19. Page, W. & Knosp,O. Hyperproduction of poly-β-hydroxybutyrate druing exponential growth of Azotobacter vinelandii UWD. Applied and Environmental Microbiology, 55,(1989).1334-1339.
20. Suzuki, T., Yamane, T., & Shimizu, S. Mass production of poly-beta-hydroxybutyric acid by fed-batch culture with controlled carbon/nitrogen feeding. Applied Microbiology and Biotechnology, 24 (1986), 370-374.
21. Adwitiya Pal, Ashwini Prabhu,Avinash Arun Kumar,Badri Rajagopal, Kajal Dadhe,Vomsi Ponnamma, Srividya Shivakumar, Optimization of process parameter for maximum poly-β-hydroxybutyrate (PHB) production by Bacillus thuringiensis IAM 12077,Polish Journal of Microbiology, Vol.58(2) (2009), 149-154.
22. Dieter Jendrossek and René Handrick, Microbial degradation of Polyhydroxyalkanoates. Annual Review of Microbiology Vol. 56 (2002), 403-432.
23. Venkateswar Reddy, M., and Venkata Mohan, S. Influence of aerobic and anoxic microenvironments on polyhydroxyalkanoates (PHA) production from food waste and acidogenic effluents using aerobic consortia. Bioresource Technology. 103(1) (2012), 313-321.
24. Coats, E.R., VandeVoort, K.E., Darby, J. and Loge F.J. Toward polyhydroxyalkanoate production concurrent with municipal wastewater treatment in a sequencing batch reactor system. Journal of Environmental Engineering. 137(1) (2011), 46-54.
25. Choi, J. & Lee, S. Process analysis and economic evaluation for Poly(3-hydroxybutyrate) production by fermentation. Bioprocess Engineering, 17(1997), 335-342. Springer Verlag.
26. Sindhu, Raveendran et al. Production and Characterization of Poly-3-hydroxybutyrate from Crude Glycerol by Bacillus sphaericus NII 0838 and Improving Its Thermal Properties by Blending with Other Polymers, Arch. Biol. Technol. v.54 n.4: pp. 783-794, July/Aug 2011).
27. N.Phanse et al., Screening of PHA (poly hydroxyalkanoate) producing bacteria from diverse sources, International Journal of Biosciences (IJB) Vol. 1, No. 6, p. 27-32, 2011 .