Title: Histopathological Pattern of Ovarian Mass Lesions in a Tertiary Care Hospital, at Muzaffarpur, Bihar
Authors: Dr Mahesh Prasad, Dr. Manoj Kumar
DOI: https://dx.doi.org/10.18535/jmscr/v7i3.41
Abstract
Objective: The aim of the present study was to identify the pattern of pathologies involving ovarian mass lesions which were received for histopathological evaluation.
Materials and Methods: A total of 126 woman of different age groups, attending in obstetrics and Gynecology OPD presenting with various gynecological complains of mucoid or mucopurulent vaginal discharge, chronic backache, lower abdominal pain, Irregular vaginal bleeding, post coital bleeding, pain during coitus and dysuria were included in study. All the data regarding age, religion, socioeconomic status, parity, and locality and presenting complains of the patients were noted. After surgery all the ovarian tissue were received in our Department for histopathological evaluation. After ensuring adequate tissue fixation, tissue slices were taken and processed. Microsections of 5 microns thickness were taken onto glass slides and stained by standard Hematoxylin and Eosin stains. After mounting and labeling smears were seen under oil immersion microscope.
Results: A total of 126 samples of ovarian tissue were received for histopathological evaluation, out of them 114 (90.47%) masses were unilateral and 12 (9.52%) were bilateral. Majority of patients 70 (55.56%) were in the age group of 21-41 years. The lesions were broadly classified as Benign Neoplastic lesions 52(41.27%), Non - Neoplastic lesions 71(56.35%) and Malignant Neoplastic lesions 3(2.38%). Follicular cysts were the predominant 36 (28.57%) non - neoplastic lesions diagnosed followed by corpus luteum cysts 20(15.87%). Serous cystadenoma was the most common benign neoplasia lesion diagnosed 34(26.98%), followed by Mucinous cystadenomas 13(10.31%)In Malignant neoplastic lesions Papillary serous cystadenocarcinoma 1 cases (0.79%), Borderline mucinous cystadenoma 1 cases (0.79%) and Granulosa cell tumor 1(0.79%) were diagnosed.
Conclusion: The majority of ovarian lesions received for evaluation were benign and unilateral. Most patients were in the third to sixth decades of life.
Keywords: Follicular cysts, Incidence of pathologies, ovarian mass lesions, serous cystadenoma.
References
- Modi D, Rathod GB, Delwadia KN, Goswami HM. Histopathological pattern of neoplastic ovarian lesions. IAIM. 2016;3(1):51-7.
- Young RH. The ovary. In: Sternberg S. Diagnostic Surgical Patholo. 17th Ed. New York: Raven Press. 1994:2195.
- Ellenson LH, Pirog EC. Ovaries. In: Robbins and Cotran- Pathologic Basis of Disease. South Asia Edition. New Delhi: Reed Elsevier India. 2014: 1022.
- Tortolero L, Mitchell FM, Rhodes HE. Epidemiology and screening of ovarian cancer. Obstet Gyanecol Clin North Am. 1994;21:63-75. Prakash A et al. Int J Adv Med. 2017 Jun;4(3):745-749 International Journal of Advances in Medicine | May-June 2017 | Vol 4 | Issue 3 Page 749
- Bhattarcharya MM, Shinde SD, Purandare VN. A clinicopathological analysis of 270 ovarian tumors. J Postgrad Med. 1980;26:103-7.
- Forae GD, Aligbe JU. A histopathological overview of ovarian lesions in Benin City, Nigeria: How common is the functional cyst? Int J Med Public Health. 2014;4:265-8.
- Pachori G, Meena US, Sunaria RK, Pachori P, Jethani N, Bayla T. Histopathological study of ovarian tumors in Ajmer region. Int J Med Sci Public Health. 2016;5:1400-3.
- Rashid S, Sarwas G, Ali A. A clinicopathological study of ovarian cancer. Mother Child. 1998;36:117 -25.
- Prabhakar BR, Kalyani M. Ovarian tumors - prevalence in Punjab. Indian J Pathol Mirobiol. 1989;32(4):276-81.
- Couto F, Nadkarni NS, Rebello MJ. Ovarian tumors in Goa. A clinicopathological study. J Obstet Gynecol of India. 1993;43(3):408-12.
- Thakkar NN, Shah SN. Histopathological study of ovarian lesions. Int J Sci Research 2015; 4(10):1745-9.
- Ramachandran G, Harilal KR, Chinnamma K, Thangavelu H. Ovarian neoplasms -A study of 903 cases. J Obstet Gynecol India. 1972;22:309 -15.
- Pilli GS, Sunitha KP, Dhaded AV, Yenni VV. Ovarian tumors - a study of 282 cases. J Indian Med Associ. 2002;100(7):420-4.