Title: Clinical Approach to Patients with Acute Viral Hepatitis A and Factors Associated with Poor Prognostic Outcome
Authors: Dr Sourav Chattopadhyay, Dr Maninderpal Singh Dhaliwal
DOI: https://dx.doi.org/10.18535/jmscr/v11i3.26
Abstract
Background: Hepatitis A is the most common infectious etiology of acute viral hepatitis. There has been an increase in incidence of disease in many parts of the world, along with more complications and many unwanted secondary effects. The main aim of study is to identify the clinical profile, unwanted secondary effects and risk factors associated with worst outcome.
Material and Methods: A Prospective observational study was conducted on 100 consecutive patients who attended the Civil Hospital, Gurdaspur, Punjab. The patients were kept under follow up for four months. Clinical evaluations and relevant investigations were conducted on those patients.
Results: Most of the patients were between 18 to 40 years. Thrombocytopenia, transverse myelitis, Loss of appetite, arthralgias , pancreatitis and acute renal injury were some of the unwanted secondary effects. Three patients died.
Conclusions: There were no correlation between SGPT levels and complications. Prior NSAID, Chemicals & alcohol intake is associated with adverse outcome.
Keywords: Acute Viral Hepatitis A, NSAIDS, Hepatic encephalopathy.
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