Title: Ganglioneuroma of Coccyx: A Case Report
Authors: Bandana Mehrotra, Shubhi Pandey Sharma, Supriya Mehrotra, Ashok Kumar Kapoor*, Alok Kumar, Aditi Dixit
DOI: https://dx.doi.org/10.18535/jmscr/v11i2.18
Abstract
A child aged 5 years female, complained of lower back pain for 5 months during defecation. Per-rectal examination revealed a swelling in retrorectal presacral region. She was operated. A tumour, measuring 8×5×5 cm was excised. Histopathological examination of the tumour revealed presence of large number of ganglion cells and schwann cells in loose myxomatous fibrillary stroma. Tumour tissue revealed positivity for S100, desmin and neuron-specific enolase (NSE). In addition, mild positive reaction (1+) was obtained with anti-Sox-10 antibody. Negative reaction was obtained with anti-Ki 67 and anti-chromogranin antibodies. Tumour was finally diagnosed as ganglioneuroma.
Keywords: Benign Ganglion cells, Schwann cells, S100 positivity.
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