Title: A Spectrum of Endometrial Histopathology in AUB- An Institutional Experience

Authors: Dr Pavan Kumar M, Dr Roopashree G, Dr Shashidhar H B

 DOI: https://dx.doi.org/10.18535/jmscr/v11i2.14

Abstract

Background: Abnormal Uterine bleeding (AUB) defined as bleeding that does not fall within normal ranges of amount, duration, frequency or cyclicity of normal menstrual pattern. AUB is associated with significant morbidity among women of various age groups.

Objectives: 1) To observe histopathological spectrum of endometriumin AUB.

2) To analyse the incidence of various endometrial histopathology associated with AUB occurring in women of different age groups.

Methodology: One year two months retrospective study was done at Department of Pathology, MMC&RI which included 150 cases of clinically diagnosed AUB. Histopathological examination of endometrium obtained from biopsy and hysterectomy specimens were clinically correlated.

Results: Out of 150 cases of AUB, common histopathological observations made were proliferative endometrium (46.7%), Secretory endometrium (23.3%), Atrophic phase (11.3%), Endometrial Hyperplasia (10.7%), Endometrial Adenocarcinoma (5.3%), Serouscarcinoma (0.7%) and threebiopsy (2%) specimens were in adequate for evaluation.

Conclusion: Based on the present study incidence of AUB was high among peri-menopausal age group associated with proliferative endometriumon histopathology. Diagnostic histopathology plays a key role in management of AUB and to rule out early malignancy.

Keywords: Endometrium, Abnormal Uterine Bleeding (AUB), Hyperplasia, Endometrial carcinoma.

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Corresponding Author

Dr Roopashree G

Senior Resident, Department of Pathology, Mysore Medical College and Research Centre, Mysore