Title: Perinatal Outcome in Meconium Stained Amniotic Fluid
Author: Dr. Manisha
DOI: https://dx.doi.org/10.18535/jmscr/v11i2.10
Abstract
Introduction
- Meconium stained amniotic fluid has long been implicated as a factor influencing fetal well being during intra-partum and post-partum periods. Obstetric Management is significantly effected by presence of Meconium Stained Amniotic Fluid (MSAF) possibility reflecting low threshold for obstetric intervention.
- Meconium-stained amniotic fluid, as a result of the passage of fetal colonic contents into the amniotic cavity, is noted in approximately 12% of all deliveries.
- Meconium aspiration syndrome (MAS) is noted in 5% of these infants and more than 4% of MAS infants die, accounting for 2% of all perinatal deaths.
There is strong evidence most meconium passage occurs by each of three basic mechanisms:
- As a physiologic maturational event.
- As a response to acute hypoxic events occurring late in pregnancy.
- As a response to chronic intrauterine hypoxia.
Many maternal factors contribute to passage of meconium before birth which include maternal age, prolonged gestation, type of labour, anemia, hypertension and toxemia of pregnancy[1.2]. Type of meconium passage and time of passage are significant factors affecting fetal outcome.
References
- Kamala Gokhroo, Usha Sharma et al, “Various maternal factors responsible for meconium stained amniotic fluid”, J. Obstetrics & Gynecology of India, 51; 6: 2001.
- Joshio Fijikura, MD, Bernard Klionsby, MD, “The significance of meconium stained”, Am. J. of Obstetrics & Gynecology, 1979.
- Miller, David A, Sacks, MD, Barry S, Schifrin MD, Edward H, Hon MD, “Significance of meconium during labour”, Am. J. Obstetrics &Gynecology, Vol. 122: 1975.
- Rosario MC, Seshadri L. Meconium staining of amniotic fluid in low risk parturients. Journal of Obstetrics and Gynaecology of India 1996; 46:642-646
- Kamala Gokhroo, Usha Sharma et al, “Various maternal factors responsible for meconium stained amniotic fluid”, J. Obstetrics &Gynecology of India, 51; 6: 2001
- Bhide SS, Shendurnikar S Aiyer, SR Baxi, “Neonatal outcome after meconium stained amniotic fluid”, J. of Obstetrics &Gynecology of India, 43; 933: 1993