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Category: Volume 11 Issue 01 January 2023
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Title: Co-infection with Hepatitis B virus (HBV) and Hepatitis C Virus (HCV) may Result in Asymptomatic Carrier Stage: A Case Report

Authors: Bandana Mehrotra, Ashok Kumar Kapoor, Hari Shyam, Atul Kumar Srivastava, Vasundhara Sharma, Supriya Mehrotra and Rajesh Kumar Srivastava

 DOI: https://dx.doi.org/10.18535/jmscr/v11i1.07

Abstract

A 45-year-old male presented with mild loss of appetite. Serum total bilirubin was 1.2 mg/dl (reference range 0.1 to 1.0 mg/dl). Serum GOT was mildly raised to 56 (reference range 10-35 IU). Serum HBsAg was positive. Serum IgM anti-HCV antibody was also positive.  The diagnosis of HBV and HCV co-infection was confirmed by Real-Time PCR. He was diagnosed as a case of asymptomatic HBV and HCV co-infection. Imbalance in the concentration of natural killer cells (NK dim and NK bright) might increase the necrosis of infected hepatocytes. Generation of cytotoxic T lymphocytes might eliminate both HBV and HCV, resulting in cell mediated immunity response and viral clearance.

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Corresponding Author

Ashok Kumar Kapoor