Title: Retinal nerve fibre layer and macular thickness in patients of migraine –an optical coherence tomography based study

Authors: Dr Luxmi Singh, Dr Aashna Agarwal, Dr Deeksha Tyagi

 DOI: https://dx.doi.org/10.18535/jmscr/v10i12.12

Abstract

Introduction: To study the correlation of Macular and RNFL thickness in relation to duration, type and severity of migraine.

Methods: The study included migraine patients with and without aura. All the study participants underwent a thorough clinical evaluation, fundus examination, visual field assessment after due consent and ethical clearance. RNFL thickness was measured using optical coherence tomography (OCT). RNFL and macular thickness was correlated with MIDAS score grading system.

Result: There is a significant association of RNFL thickness in nasal segments in association with MIDAS score grading. (p=0.05)

Macular thickness at VC was significantly thinner in those with <1 year disease as compared to patients having disease for 2-5 years and >5 years.

Conclusion: Significant association of RNFL thickness in nasal segments in association with MIDAS score grading. (p=0.05)

Further studies are required to further investigate the relationship between migraine and macular/RNFL thickness.

Keywords: Retinal nerve fiber layer; macular layer; migraine; OCT; MIDAS score grading.

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Corresponding Author

Dr Aashna Agarwal

Junior Resident, Department of Ophthalmology, Era’s Lucknow Medical College and Hospital, Era University, Lucknow, Uttar Pradesh, India