Title: A Rare Case of MOG Antibody Disease
Authors: Dr Deepsheeka.G, Dr Aravind Kumar.V, Dr Badrinath.A.K
DOI: https://dx.doi.org/10.18535/jmscr/v10i11.13
Abstract
Myelin oligodendrocyte glycoprotein antibody disease (MOGAD) consists of a group of inflammatory demyelinating disorders. Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) covers a wide spectrum of manifestations and is defined by the presence of MOG seropositivity. However, in a proportion of patients, there may be an overlap in some of the clinical and radiological manifestations between MOGAD and multiple sclerosis (MS) or Neuromyelitis optica .Being wary of this entity is critical to ensure appropriate therapy. We present a case report of MOGAD, who along with longitudinally extending transverse myeltis had optic neuritis.
Keywords: case report, myelin oligodendrocyte glycoprotein antibody, multiple sclerosis, transverse myelitis, optic neuritis, NMO.
References
- Makkar S, Ahuja N, Khandelwal S. A rare case of myelin oligodendrocyte glycoprotein antibody disease with keratoconus. Indian J Ophthalmol Case Rep 2022;2:23-5.
- Kister EP. The Expanding Clinical Spectrum of Myelin Oligodendrocyte Glycoprotein (MOG) Antibody Associated Disease in Children and Adults. Frontiers in Neurology. 2020 Sep 9;
- Yang Zheng, Meng-Ting Cai ,Er-Chuang Li ,Wei Fang,Chun-Hong Shen and Yin-Xi Zhang. Case Report: Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disorder Masquerading as Multiple Sclerosis: An UnderRecognized Entity? Frontiers in Neurology [Internet]. 2017 Spring 6; Available from: http://dx.doi.org/10.3389/fimmu.2021.671425