Title: A Comparative Clinical trial on trophic ulcers of Leprosy: Ayurvedic management was promising!

Authors: Dr. Sarita Pradip Gaikwad M.D. (Manas rog), PhD (Kayachikitsa), Maj. Dr. Pradip Gaikwad, M.D. (PSM), D.P.H. (AIIHPH, Calcutta)

 DOI: https://dx.doi.org/10.18535/jmscr/v10i8.11

Abstract

Introduction: Trophic ulcers in Leprosy patients is the major cause of disability. Ulcer Management by Modern Western Medicine has remained far from effective.

Aim: To examine the effect of Ayurvedic treatment on healing of trophic ulcers vis a vis conventional treatment.

Methodology: A non randomized comparative clinical trial on trophic ulcers in leprosy was undertaken. There were 31 study subjects selected from Dr. Bandorawalla Leprosy Hospital, Kondhwa and there were 31 subjects from two leprosy homes as control group. Criteria of selection of the patient was the age of planter ulcer was > 1 year. The study subjects were given Ayurvedic treatment and the control subjects were treated by conventional line of treatment. The area of ulcer of study group was 5.5 times more than the size of control group subjects.

Results: There was 76.84% improvement was noted in study group while in control group there was 43.24% improvement noted and further the average size of ulcer increased by 1.52%. In study group 89.47% ulcers showed more than 50% improvement as 34/38 ulcer showed the improvement, χ2= 16.00, p<0.001 Statistically Highly significant.

Conclusion: The study proved that the Ayurvedic treatment may be a better alternative for treating trophic ulcers in Leprosy.

Keywords: Trophic ulcers in Leprosy, Ulcer management in Leprosy, Mahakushta, Ayurvedic management of Dushtavrana.

References

  1. Leprosy-WHO/ World Health Organization. https://www.who.int/news-room/fact-sheets/detail/leprosy#:~:text=Untreated%2C%20leprosy%20can%20cause%20progressive,629%20children%20below%2015%20years.
  2. Santoshdev P. Rathod, Ashish Jagati, and Pooja Chowdhari. Disabilities in leprosy: an open, retrospective analysis of institutional records. An Bras Dermatol.2020 Jan-Feb; 95(1): 52–56.
  3. Nayak A.K., Satheesh R., Shashidhar K. Spectrum of physical deformities in leprosy patients visiting a tertiary care center in Mangalore. Ann Trop Med Public Health. 2017;10:22–26. [Google Scholar]
  4. Mankar S, Kawalkar A, Sakhare R, et al. Posterior Tibial nerve neurolysis for treatment of leprosy induced planter ulcers. Journal of Trauma and Orthopaedic Surgery. 2020; 15 (2) : 27-30. 
  5. Vinita Puri, N Venkateshwaran, Nishant Khare. Trophic ulcers-Practical guidelines. Indian J Plast Surg 2012; 45(02): 340-351
  6. Sarita Gaikwad and Pradip Gaikwad: Effect of Ayurvedic treatment on trophic ulcers of Leprosy- A comparative clinical trial. Aryavaidyan Vol. 23 (3), Feb-Apr. 2010. p: 139-143
  7. Suryawati N, Praharsini I G A A, Juliyanti J. Management Non-healing Trophic Ulcer in a Leprosy Patient with Combination of Injection and Topical Platelet Rich Plasma. J Skin Stem Cell. 2019;6(3):e101432.
  8. Editor Anantram Sharma. Sutrashtan Chapter 23 verse 7 in Sushruta Sanhita. Chaukhamba Surbharti Prakashan, Varanasi-221001(India). 2015:197
  9. Editor Vaidya Indradeo Tripathi. Chapter Vata in Vanaushadhidarpanah. Chowkhamba Sanskrit Series Office, Varanasi-221001(India). Ist edition. 2006:294-296
  10. Editor Vaidya Indradeo Tripathi. Chapter Udumbar in Vanaushadhidarpanah. Chowkhamba Sanskrit Series Office, Varanasi-221001(India). Ist edition.2006:57-60
  11. Editor Vaidya Indradeo Tripathi. Chapter Ashwattha in Vanaushadhidarpanah. Chowkhamba Sanskrit Series Office, Varanasi-221001(India). Ist edition. 2006: 29-31
  12. Editor Vaidya Indradeo Tripathi. Chapter Mustakah in Vanaushadhidarpanah. Chowkhamba Sanskrit Series Office, Varanasi-221001(India). Ist edition.2006:364-367
  13. Editor Vishwanath Dwivedi. Chapter Haritkyadivargah in Bhavprakash Nighantu. Motilal Banarasidas, Varanasi-221001(India). 8th1974:11
  14. Editor Vaidya Indradeo Tripathi. Chapter Haritaki in Vanaushadhidarpanah. Chowkhamba Sanskrit Series Office, Varanasi-221001(India). Ist edition. 2006:429-435
  15. Editor Vaidya Indradeo Tripathi. Chapter Haridrachatustayam in Vanaushadhidarpanah. Chowkhamba Sanskrit Series Office, Varanasi-221001(India). Ist edition.2006: 435-437

Corresponding Author

Dr. Sarita Pradip Gaikwad M.D. (Manas rog), PhD (Kayachikitsa)

Director, Punarnava Trimarma Chikitsalay and Research Centre, Nanded-431 602 (India)

Ex HoD Ayurved Research Department, Sassoon Hospital, Pune-411 001 and  

Vol. Retd. Assistant Director, AYUSH, Pune region, Pune