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Category: Volume 10 Issue 08 August 2022
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Title: Role of prophylactic antibiotics in elective laparoscopic cholecystectomy surgical site infection

Authors: Jan Mohammad Rather, Javaid Iqbal, Sobia Manzoor

 DOI: https://dx.doi.org/10.18535/jmscr/v10i8.10

Abstract

Backgrounds: Laparoscopic cholecystectomy is a widely used procedure. The use of prophylactic antibiotics in elective laparoscopic cholecystectomy is debatable. The aim of this study is to study whether prophylactic antibiotics could prevent surgical site infection after elective laparoscopic cholecystectomy and to identify any risk factors for surgical site infection.

Methods: This study included 300 patients undergoing laparoscopic cholecystectomy between January 2009 and May 2012. Group A patients (180) received third generation cephalosporin 1 g intravenously after induction of anesthesia, and group  B patients (120) were not given prophylactic antibiotics. The surgical site infection rates of the patients were compared and analyzed among the two groups.

Results: The overall rate of surgical site infection was 1.69% for the total of 300 patients. The incidence of surgical site infection was similar for the two groups: 4 of 180 patients (2.22%) in Group A, 3 of 120 patients (2.5%) in Group B (p=0.913). All of the patients with surgical site infections were well treated under conservative treatments without any sequelae. The preoperative albumin level (p=0.027) contributed to surgical site infection.

Conclusions: Prophylactic antibiotics have no role for elective laparoscopic cholecystectomy except for patients with poor nutritional state.

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Corresponding Author

Jan Mohammad Rather