Title: A Case Series Discussing Anesthetic Considerations and Statistical Analysis between Rhino-Orbital Mucor-mycosis with Convalescent COVID-19 Status

Author: Dr Vaijayanti Nitin Gadre

 DOI: https://dx.doi.org/10.18535/jmscr/v10i4.07

Abstract

Introduction: Rhino Orbital Mucor Mycosis (ROMM) cases were witnessed recently in large numbers. This condition was commonly seen in patients who had recovered from COVID-19 in the previous 3 to 6 months period. The aim to present this case series is to find out ifRhino Orbital Mucor Mycosis (ROMM) in COVID-19 recovered patients are related conditions and whether the pre-existing morbid conditions worsen the clinical picture.

Methods: All cases of ROMM for Functional Endoscopic Sinus Surgery (FESS) that presented in our tertiary centre (January to June 21) were sequentially included. Patients (21 to 80 years) of both genders were 99 in number. Patients with uncontrolled systemic condition and COVID positive status were excluded till optimized and/or became COVID negative. Patients underwent optimization of presenting clinical condition from respective departments. Balanced general anaesthesia with endotracheal intubation and controlled ventilation was administered. Patients with diagnosed lower severity of ROMM were extubated on table and those with orbital and neural extension were electively ventilated; also major associated cardiovascular, neurological, renal or respiratory cases were ventilated post-operatively for gradual weaning.

Results: Patients were compared in six groups according for oxygen status, oxygen requirement, pre-existing co-morbidities, CT Severity Score, CT Brain findings and intubation difficulty. Oxygen therapy by Non Re-breathing Bag Mask (NRBM) showed P- value 0.029 (statistically significant) and that of intubation difficulty was 0.29 which are statistically not insignificant.

Conclusion: The five studied variables are independent and do not contribute to having COVID history as per this analysis.

Keywords: Statistical Analysis, Rhino Orbital Mucor Mycosis (ROMM), Convalescent COVID-19 Status

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Corresponding Author

Dr Mrs. Vaijayanti Nitin Gadre