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Category: Volume 10 Issue 01 January 2022
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Title: Antimicrobial Resistance Profile of Uropathogenic Gram Negative Bacteria

Authors: Ishrat, Parveen Naaz, Dr Ashok Rattan, Bharti, Saleha Naseem

 DOI: https://dx.doi.org/10.18535/jmscr/v10i1.35

Abstract

UTIs are one of the common illness in the worldwide, affecting people of all ages, with females having the highest prevalance. The study investigate the drug resistance profile of the uropathogenic bacterial isolate from study region antibiotic. The study aims to describe guidelines for empiric UTI treatment in the current context, when antibiotic resistance patterns are shifting.

Aim: The Aim of this study is to identify gram negative pathogen associated with UTI in certain districts of UP and Bihar with the help of retrospective data from referral lab in the districts having no or very low microbiological lab facilities.

Method: This study was carried out in the department of microbiology's bacteriology laboratory from January 2019 to December 2020. (Pathkind, NABL Accrediated lab).To attain the stated goals, the investigation employed a retrospective study design. All urine cultures are included in the research. Use SPSS software to analysis data. Urine cultured positive, organism isolates and their antibiotic resistance profile for UTI included as variables

Results: Overall, 19546 urine samples were received in 2019 and 29785 samples received in 2020.Out of which 2521 urine samples were isolates in 2019.Out of which 202 sample were gram positive whereas 2319 samples were gram negative Among the bacterial isolates all were gram-negative. The most common bacteria isolated were E.coli

Conclusion: Antibiotic therapy for infections should be based on local experience of sensitivity and resistance patterns since bacterial resistance to specific antibiotics evolves over time and in various regions. Antibiotic resistance is prevalent, especially to ampicillin, cefuroxime, ampicillin sulbactam, and cefuroxime.

Keyword: Uropathogens; antibiotic resistance.

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Corresponding Author

Ishrat