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Category: Volume 09 Issue 12 December 2021
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Title: Effects of Vitamin E and Mefenamic Acid in the Treatment of Primary Dysmenorrhoea in Tertiary Care Hospital in Bangladesh

Authors: Dr Kanika Roy, Dr Biplab Kumar Das

 DOI: https://dx.doi.org/10.18535/jmscr/v9i12.29

Abstract

Background: In various research, vitamin E and mefenamic supplementation has been suggested as a viable treatment for primary dysmenorrhea.

Objective: To see the effects of Vitamin E and mefenamic acid in primary dysmenorrhoea.

Methods: Sheikh Sayera Khatun Medical College and Hospital, Gopalganj conducted this observational type of prospective study. Where information was gathered between 1st April 2019 to 31st March 2020. During the research, a total of 40 Female OPD patients in Sheikh Sayera Khatun Medical College and Hospital, Gopalganj, who fulfilled the selection criteria were the study sample. Purposive sampling was used to acquire the samples according to the inclusion criteria. All data were coded and entered into SPSS-23 for further analysis. The statistics used were both descriptive and inferential. Statistics used to describe data included frequency distribution, percent, mean, and standard deviation; graphs; tables; and figures; and inferential statistics.

Results: VAS score was significantly decreased from baseline to end of treatment at 3rd cycle (7.40 ± 0.98 to 3.70 ± 0.72) for vitamin E group and (7.05 ± 0.75 to 3.52 ± 0.55) for mefenamic acid group. The percentage reduction of VAS was 49.60% and 49.51% at 3rd cycle. The Cox Menstrual Symptom Scale score significantly decreased from baseline to end of treatment at 3rd cycle (3.88 ± 0.40 to 1.25 ± 0.44).The percentage reduction of CMSS score was 67.50% and 65.83% at 3rd cycle.

Conclusion: As both Vitamin E and Mefenamic acid shows significant reduction in pain intensity in primary dysmenorrhoea without any difference between two treatment groups. So, in clinical practice, Vitamin E may be a useful alternative to Mefenamic acid in primary dysmenorrhoea.

Keywords: Primary dysmenorrhoea, Mefenamic acid, Vitamin E.

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Corresponding Author

Dr Kanika Roy

Senior Consultant, Department of Gynae and Obstetrics, 100 Bedded Upazila Health Complex, Kashiani, Gopalgonj, Bangladesh