Title: Management of Oesophageal Cancer: A 3 Years Retrospective and 1 ½ years Prospective Analysis

Authors: Dr Shrikant Sudam Suryawanshi, Dr Saia Chenkula, Dr John Zohmingthanga, Dr Zothansanga Ralte

 DOI: https://dx.doi.org/10.18535/jmscr/v9i9.04

Abstract

Background: In India, Oesophageal cancer is second most common cancer among males and fourth most common among females and is associated with certain diets and lifestyle.

Aim: To study the management protocol and post-operative complications of oesophageal cancer patients at Civil Hospital, Aizawl.

Methods: A Descriptive study (3 years retrospective and 1½years prospective) was conducted at Civil Hospital, Aizawl, Mizoram from July 2013 to December 2014 (1 ½  years) amongst 104 patients reporting to Civil Hospital, Aizawl for oesophageal cancer.

Results: Histopathological examination of rescted esophageal specimen showed 95.71% patients were detected with Squamous cell carcinoma, 4.29% patients were detected with no proper malignancy/residual tumor. Transhiatal Oesophagectomy (THE) + Gastric pull up (GPU) + Feeding Jejunostomy (FJ) was common (37%) surgical management procedure was done in patients.

Conclusion: Results of present study suggest that squamous cell carcinoma is the major histologic type found in esophageal cancer patients. Most of patients presented in advance stage and had grave prognosis.

Keywords: Dysphagia, Squamous cell carcinoma, Oesophagus.

References

  1. Law S. Cancer of oesophagus. 12th ed. Zinner M, Ashley S:Maingot s abdominal operations; 2013.
  2. Sinha R, Anderson DE , McDonald SS, Greenwald P. Cancer risk and diet in India. J Postgrad Med. 2003 Jul-Sept ;49(3):222-8.
  3. Alderson D. The Oesophagus. 26th ed. Williams NS, Bulstrode CJK, O’Connell PR: Bailey and Love’s Short Practice of Surgery;2013.
  4. Rai G. Clinicopathological study of cancer oesophagus. Mangalore: Rajiv Gandhi University of Health Sciences, Karnataka. 2012.
  5. National Cancer Registry Programme. Two year report of the Population Based Cancer Registries Under North Eastern Regional Cancer Registry 2005-2006. Bangalore:Indian Council Of Medical Research; 2007.
  6. Civil Hospital, Aizawl Medical Records.
  7. W Hu, Y Liang, S Zhang,Y Hu, J Liu. Ten-year survival of patients with oesophageal squamous cell carcinoma. S Afr J Surg 2013;51(2):62-66.
  8. Jian-Yang Ma, Zhu Wu, Yun Wang, Yong-Fan Zhao, Lun-Xu Liu, Ying-Li Kou, Qing-Hua Zhou. Clinicopathologic characteristics of esophagectomy foresophageal carcinoma in elderly patients. World J Gastroenterol 2006 February 28; 12(8):1296-1299
  9. Nozoe T, Saeki H, Ohga T, Sugimachi K. Clinicopathological characteristics of oesophageal squamous cell carcinoma in young patients. Ann Thorac Surg. 2001;72:1914 –17.
  10. Kirtika Patel, Johnston Wakhisi, Simeon Mining, Ann Mwangi and Radheka Patel. Esophageal Cancer, the Topmost Cancer at MTRH in the Rift Valley, Kenya, and Its Potential Risk Factors. Hindawi Publishing Corporation ISRN Oncology;2013:2-3
  11. Khan NA, Maqbool LM, Afroz F, Kharadi MY. Clinicopathological profile of carcinoma oesophagus and oesophagogastric junction in Kashmir. JK-Practitioner. 2004;11(3):182-185.
  12. Kuwano H, Nakajima M, Miyazaki T, Kato H. Distinctive clinicopathological characteristics in oesophageal squamous cell carcinoma. Ann Thorac Cardiovasc Surg. 2003 Feb;9(1):6-13.
  13. Su D, Zhou X, Chen Q, Jiang Y, Yang X, Zheng W, Tao K, Wu J, Yan Z, Liu L, Wu S, Mao W. Prognostic nomogram for thoracic esophageal squamous cell carcinoma after radical esophagectomy. PLoS One. 2015 Apr 20;10(4):e0124437

Corresponding Author

Dr. Shrikant Sudam Suryawanshi

(MBBS, DNB General Surgery, MCh CVTS)

Assistant Professor, Department of CVTS, L.T.M.G Hospital and Medical College, Sion, Mumbai