Title: To Estimate Serum Testosterone in Patients of Diabetes Type 2 Having Metabolic Syndrome

Authors: Dr Sushmita, Dr Gaurav Chaudhary, Dr Surya Prakash

 DOI: https://dx.doi.org/10.18535/jmscr/v9i8.23

Abstract

Objective:  To estimate serum testosterone level in male patients of diabetes type 2 having metabolic syndrome.

Background: Major public health issue faced by the world in present century is diabetic mellitus and the prevalence is also increasing explosively, low testosterone levels in men is one of the diabetic related complication.

Methods: This was a prospective population based study of sixty seven diabetic male patients aged 36 – 70 years (median 56.36= 10.26) reaching emergency and OPD having metabolic syndrome and were evaluated for serum testosterone levels.

Results:  sixty Seven male patients with type 2 diabetes mellitus were enrolled during the study period. The mean age of study population was 56.36±10.26 years (range 36-70), while that of control group patients was found to be 39.80±7.92years. The total number of patients who had BMI of more than 25 kg/ m2, were 19 and all these have low levels of testosterone (<241 ng/dl) which is significant (p value <0.001) .Total number of patient having triglyceride level> 150 mg/dl were 17 and all these have low levels of testosterone which is significant (p value <0.001) The mean HbA1c in study group was 8.83±1.95 %, which was significantly higher as compared to control group with HbA1c 4.82±0.40.

Conclusions: The present study highlighted that significant difference in serum total testosterone level has been observed in patients of metabolic syndrome (X2 =55.7, P=0.0001).

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Corresponding Author

Dr Sushmita

Senior resident KPS Institute of General Medicine Kanpur