Title: Adenocystic Carcinoma Palate with Lung Metastasis- A Case Report and Review of Literature
Authors: Tarun Kumar, Simrandeep Singh, Hemendra Mishra, Kapil Suri, Rajiv Sharma
DOI: https://dx.doi.org/10.18535/jmscr/v9i6.37
Abstract
Background
Tumors of the minor salivary gland origin are uncommon, accounting for about 2% to 3% of all malignant neoplasms of the upper aerodigestive tract1. Although adenocystic carcinoma (ACC) are common entity among salivary gland tumors but still very less number of cases are reported with lung metastasis. Also ACC is known to show delayed distant metastasis. Due to limited data on ACC with lung metastasis, a lacunae lies in how to manage metachronous lung metastasis after the complete remission of local disease. In this study we report a case report of ACC hard palate with recurrence of lung metastasis after 10 years of locoregional treatment along with review of literature.
References
- Devitapg 1077
- Bjørndal K, Krogdahl A, Therkildsen MH, et al. Salivary gland carcinoma in Denmark 1990–2005: a national study of incidence, site and histology.Results of the Danish Head and Neck Cancer Group (DAHANCA)Oral Oncol 2011;47:677–682.
- Devitapg 1077
- Spiro R. Salivary neoplasms: overview of a 35-year experience with 2,807 patients. Head Neck Surg1986;8:177–184.
- Terhaard CH, Lubsen H, Van der Tweel I, Hilgers FJ, Eijkenboom WM, Marres HA, Tjho-Heslinga RE, de Jong JM, Roodenburg JL; Dutch Head and Neck Oncology Cooperative Group. Salivary gland carcinoma: independent prognostic factors for locoregional control, distant metastases, and overall survival: results of theDutch head and neck oncology cooperative group. Head Neck. 2004 Aug;26(8):681-92;discussion 692-3.
- Seok J, Lee DY, Kim WS, et al. Lung metastasis in adenoid cystic carcinoma of the head and neck. Head & Neck. 2019;41.
- Girelli L, Locati L, Galeone C, Scanagatta P, Duranti L, Licitra L, Pastorino U. Lung metastasectomy in adenoid cystic cancer: Is it worth it? Oral Oncol. 2017 Feb;65:114-118.
- Bobbio et al. / European Journal of Cardio-thoracic Surgery 33 (2008) 790—793.
- LocatiLD,Guzzo M, bossip, et al. Lungmetastasectomy in adenoid cystic carcinoma (ACC) of salivary gland. Oral Onco!2005;41(9): 890-4.
- Hill ME, Constenla DO, A’Hern RP, et al. Cisplatin and 5-fl uorouracil for symptom control in advanced salivary adenoid cystic carcinoma. Oral Oncol 1997; 33: 275–78.
- Epirubicin, Cisplatin and Protracted Venous Infusion 5-Fluorouracil Chemotherapy for Advanced Salivary Adenoid Cystic Carcinoma Ross, P.J. et al.Clinical Oncology, Volume 21, Issue 4, 311 – 314.
- Laurie SA, Licitra L. Systemic therapy in the palliative management of advanced salivary gland cancers. J Clin Oncol. 2006;24(17):2673–8.
- Hitre E, Budai B, Takacsi-Nagy Z, Rubovszky G, Toth E, Remenar E, et al. Cetuximab and platinum-based chemoradio- or chemotherapy of patients with epidermal growth factor receptor expressing adenoid cystic carcinoma: a phase II trial. Br J Cancer. 2013; 109:1117–22.
- Glisson B, Blumenschein G, Francisco M, et al: Phase II trial of gefitinib in patients with incurable salivary gland cancer. J Clin Oncol 23:580S, 2005.
- Phase II study of cisplatin and imatinib in advanced salivary adenoid cystic carcinoma Ghosal, Niladri et al.British Journal of Oral and Maxillofacial Surgery, Volume 49, Issue 7, 510 – 515.
- Chintakuntlawar, A.V., Okuno, S.H. & Price, K.A. Systemic therapy for recurrent or metastatic salivary gland malignancies. Cancers Head Neck1, 11 (2016).
- Ricco, A., Davis, J., Rate, W. Et al.Lung metastases treated with stereotactic body radiotherapy: the rssearch® patient Registry’s experience. Radiat Oncol 12, 35 (2017).
- Local Therapy for Metastatic Salivary Adenoid Cystic Carcinoma: A Surveillance, Epidemiology, and End Results and National Cancer Data Base Analysis mcdermott, J. Et al. International Journal of Radiation Oncology • Biology • Physics, Volume 94, Issue 4, 953.