Title: Diagnostic Value of WBC, CRP, Procalcitonin in Acute Appendicits
Authors: Dr Manikandan G, Dr Chandrashekar N, Dr Jagannath, Dr Sharath T R
DOI: https://dx.doi.org/10.18535/jmscr/v9i4.08
Abstract
Aims and Objectives
- To analyze the diagnostic value of WBC count, C REACTIVE PROTEIN and PROCALCITONIN in acute appendicitis.
- To determine the WBC count, C reactive protein and Procalcitonin values in Acute appendicitis.
- To evaluate sensitivity, specificity, positive predictive value,negative predictive value of WBC count, C reactive protein, Procalcitonin in acute appendicitis.
Materials and Methods: A sample of 42 patients were selected using universal sampling and a prospective study was conducted. The patients with right iliac fossa pain and symptoms of acute appendicitis at the department of General surgery of Sri Siddhartha Medical College Hospital and research Centre from September 2018 to April 2020. Then the sample is subjected to WBC count, CRP, Procalcitonin levels and Histopathological report. Then the sensitivity, specificity, PPV and NPV of the above mentioned parameters are assessed.
Conclusion: We found that elevated serum CRP, Procalcitonin levels and WBC support the surgeon’s clinical diagnosis. We recommend CRP and procalcitonin measurement as a routine laboratory test in patients with suspected diagnosis of acute appendicitis. And we suggest that patients with lower abdominal pain and not clinically convincing and in the absence of increased inflammatory markers to undergo further imaging.
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