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Category: Volume 08 Issue 12 December 2020
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Title: A Case of Sodium Valproate Induced Thrombocytopenia

Authors: A. Kiruthika, S. Nakeerar, V. Venkatesh Mathan Kumar, P. Poorna Chandrika

 DOI: https://dx.doi.org/10.18535/jmscr/v8i12.35

Abstract

 

Sodium valproate is an anti-epileptic medication and is commonly used drug in psychiatric practice which has many indications. Apart from its most common side effects and its teratogenic properties, its haematological side effect needs careful monitoring and evaluation. Acquired platelet function defects have been found and attributed to this drug1,and there have been  reports of haemorrhages, prolonged bleeding time and thrombocytopenia in patients on sodium valproate with other anticonvulsant drugs2,3. Thrombocytopenia has been reported in 6–33% of adults receiving valproic acid4. Here we report a case who developed thrombocytopenia after sodium valproate monotherapy

Keywords: valproate, thrombocytopenia.

References

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Corresponding Author

A. Kiruthika

Junior Resident, Madras Medical College