Title: Lipomatous Pleomorphic Adenoma: A Rare Case Report

Authors: Dr Vaishali A Nandkhedkar, Dr Jyoti D Bhavthankar, Dr Mandakini S Mandale, Dr Jayanti G Humbe, Dr Savita P Wagh

 DOI: https://dx.doi.org/10.18535/jmscr/v8i10.14

Abstract

Pleomorphic adenoma (P A) is a benign salivary gland tumour characterized by cellular and architectural pleomorphism presented as histological heterigenity with chondroid, myxoid or osseous components. Lipomatous differentiation is a rarely observed in PA. Here we are presenting a case report of PA with striking lipomatous differentitation, located in upper lip. Recognition of such rare subtype of PA is important for clinical management. As it is located in upper lip should be considered for the differential diagnosis of Adnexal tumour.

Keywords: PA, LPA, Adnexal tumour, Salivary gland tumour.

References

  1. MNH Khandkar, S M A Sadat, T. Rahman et al. clinical presentation and histological  variation  of   pleomorphic  adenoma   of  salivary  giands,  Journal  of   Bangladesh  college  of  Physician and surgeons  37, no.2, April 20190
  2. Dardick pleomorphic  adenoma (Benign mixed   tumour )  Text of Salivary Gland  Tumour Pathology, Igaku Shoin, Tokyo 1996,75-92
  3. Mahmood Jahagir Nezhad, Saedeh Atarbashimaghden, Sepidemokhtari   et al    Different  Histopathological  feature  of pleomorphic adenoma  in  Salivary glands Inter. Journal  of oral and   Maxillofacial Pathology   2013, 4(2),  7-11
  4. M. Palma, L.M. Barin ,F.M. Pillusky et al pleomorphic adenoma with lipomatous metaplasia in hard palate:rare case report   journl of oral and maxillofacial surgery, medicine and pathology  xxx 2017630 no of 4.
  5. Musayev, B. Önal, A. Hasanov, and I. Farzaliyev, “Lipomatous pleomorphic adenoma in the hard palate :report of a rare case with cytohisto correlation and review  J. Cytol. 2014 , 31:36-9 (database)
  6. Seifort, K. Donath and R.Schafer Lipomatouspleomorhic adenoma of the parotid gland . classification of lipomatous Tissue in Salivary Glands  Pathol.Res. pract.195 :247-252 (1999)
  7. Sonal shah and Tamer  ZayedMoustafa  Case report – An unusal  variants of common palatal  salivary  gland tumour  , case report s  of pleomorphic  adenoma  with  significant  lipomatous metaplasia . case reports in dentistry   2018, Article  Id  2052347, 5 page
  8. Agaimy, “Fat-containing salivary gland tumors: a review,” Head and Neck Pathology, vol. 7, Supplement 1,pp. 90–96 2013
  9. D. Haskell, K. M. Butt, and S. B. Woo, “Pleomorphic adenomawith extensive lipometaplasia: report of three cases,”The American Journal of Surgical Pathology, vol. 29, no. 10,pp. 1389–1393, 2005.
  10. Kondo, “A case of lipomatous pleomorphic adenoma in theparotid gland: a case report,” Diagnostic Pathology, vol. 4,no. 1, p. 16, 2009.
  11. Ide and K. Kusama, “Myxolipomatous pleomorphic adenoma:an unusual oral presentation,” Journal of Oral Pathology& Medicine, vol. 33, no. 1, pp. 53–55, 2004
  12. Ide, A.Tanaka, k. kusama CASE REPORT Further evidence for adipocytic differentiation by the neoplastic myoepithelium. J. Oral patho Med (2007) 36:187-9
  13. Leroy, A. Wacrenier, D. Augusto, E. Leteurtre, A. Desaulty,and B. Gosselin, “Lipomatous pleomorphic adenoma of theparotid,” Annales de Pathologie, vol. 22, no. 3, pp. 219–221,
  14. Kiciński, B. Mikaszewski, and C. Stankiewicz, “Risk factorsfor recurrence of pleomorphic adenoma” Otolaryngologia Polska,vol. 70, no. 3, pp. 1–7, 2016.
  15. Kenichi Matsuzaka, Hideki Fukumoto, etal Lipomatous Pleomorphic  adenoma in Palatine Gland   Oral Med Pathl(2003)140
  16. Ng W K and Ma L. Pleomorphic  adenoma with extensive  Histopathology 1995 , 27,285-8
  17. Siddaraju N  Singh N  Muniraj  F, Jothilingum P.kumar  et al. Pre operativecytodiagnosis of pleomorphic adenoma with  extensivelipometaplasia  a  case report ACTA  CYTOL 2009 , 53 ,
  18. Sonti Sulochana , Madavan Manoha ran, Anitha.      Chondroid   Syringoma   -An   unusal  presentation.  Journal   Of  Clinical  and  diagnostic  Research   2014 ,   Jul   8  (7) FD13-FD 14.

Corresponding Author

Dr Vaishali A Nandkhedkar

Assistant Professor, Department of Oral Pathology and Microbiology, Government Dental College & Hospital Aurangabad Maharashtra