Title: Clinical Course, Risk Factors and Health Outcome of in patients with COVID-19: An Evidence from COVID-19 Dedicated Mugda Medical College and Hospital in Bangladesh

Authors: Dr Irin Hossain, Dr Shah Golam Nabi Tuhin, Dr Ashekur Rahman Mullick, Prof. Dr Manzurul Haque Khan, Dr M M Aktaruzzaman, Dr Md. Shafiur Rahman, Dr Md Shahin

 DOI: https://dx.doi.org/10.18535/jmscr/v8i9.39

Abstract

The outbreak of the novel corona virus disease 2019 (COVID-19) began in Wuhan, China in December 2019. Since then, it has rapidly spread around the world. The clinical spectrum of COVID-19 pneumonia ranges from mild to critically ill cases. In this study, we tried to present details of patients admitted to the COVID-19 dedicated Mugda Medical College and Hospital in Dhaka, Bangladesh with laboratory-confirmed COVID-19 and a definite clinical outcome (death or discharge) as of June 30, 2020. We conducted a retro-prospective study of 384 patients admitted with COVID-19. Epidemiological, demographic, clinical, treatment, and outcome data were obtained from patient charts and the hospitals’ admission records using a structured questionnaire. Among them 384 of the PCR confirmed COVID-19 cases had an outcome of death (25.5%), transfer to other facilities (3.1%), discharge through palliative purpose (1.6%) or live discharge (67.2%). Males accounted for 52.9% of the study subjects and 44.4% of the survivors. Survival was significantly higher in females than in males (p ≤0.001). The most common symptoms on admission were fever (21, 70.6%) and cough (229, 59.6%), followed by shortness of breath (200, 52.1%), fatigue (152, 39.6%) and sore throat (141, 36.7%). In-hospital death was higher in patients with diabetes or hypertension. Moving forward, we hope to continue to deliver early and optimal care, limit community transmission, and tying the case fatality to the lower end of the known range.

Keywords: Clinical Course, Risk Factors, Health Outcome, COVID-19 Pandemic

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Corresponding Author

Dr Irin Hossain, Dr Ashekur Rahman Mullick

National Institute of Preventive and Social Medicine (NIPSOM), Dhaka, Bangladesh