Title: Comparing long-term outcome of Traumatic Brain Injury by impact score in the ED with Glasgow outcome score

Authors: Dr Vernica Kala, Dr Suraj Horakeri, Dr Sagar Sinha, Dr Dattatray Bhusare

 DOI: https://dx.doi.org/10.18535/jmscr/v8i9.27

Abstract

Introduction

  • Traumatic brain injury has been associated with severe outcomes including vegetative states, significant disability, residual neurological deficits and assisted living. These have a major impact on quality of life of head trauma survivors. Unfavourable outcomes are routinely assessed by the Glasgow Outcome Scale (GOS), but it is not a prognostic score. Prognostic models are useful for several reasons. Clinically, they help doctors make better decisions about treatment. IMPACT SCORE (International Mission for Prognosis and Analysis of Clinical Trials in TBI) is a prognostic score to predict the long-term outcome in TBI. IMPACT score was developed by impact research group over the past several years using a large database that includes data from eight randomized controlled trials and three observational studies.This score will be calculated in an emergency room in Indian setting by using clinical parameters.This score will be correlated with short term morbidity outcomes and long-term outcome by the Glasgow outcome score.

Short term morbidity will be assessed by ;

  • Need for ventilation in first five days
  • Need for Operative treatment in the first five days
  • Need for ICU stay for 5 or more days
  • Presence of seizure in first 5 days
  • Nausea vomiting in first 5 days

Long term outcome will be assessed by the Glasgow outcome score.

Aim and Objective of the Study

  1. To calculate the impact score based on clinical parameters in Emergency room and to prove that it helps in estimating long term outcome after traumatic brain injury.
  2. Comparing impact score results with morbidity markers and Glasgow Outcome Scale.

References

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  3. Jennett B, Teasdale G, Braakman R, Minderhoud J, Knill-Jones R (1976) Predicting outcome in individual patients after severe head injury.
  4. Hernandez AV, Steyerberg EW, Taylor GS, Marmarou A, Habbema JD, et al. (2005) Subgroup analysis and covariate adjustment in randomized clinical trials of traumatic brain injury: a systematic review. Neurosurgery 57: 1244–1253.
  5. Maas AI, Marmarou A, Murray GD, Teasdale SG, Steyerberg EW (2007) Prognosis and clinical trial design in traumatic brain injury: the IMPACT study. J Neurotrauma 24: 232–238.
  6. Murray GD, Butcher I, McHugh GS, Lu J, Mushkudiani NA, et al. (2007) Multivariable prognostic analysis in traumatic brain injury: results from the IMPACT study. J Neurotrauma 24: 329–337.

Corresponding Author

Dr Vernica Kala

Second- year MD Resident, Emergency Medicine, MGM Medical College and Hospital, Navi Mumbai, India