Title: A randomized control study of preoperative fasting and oral glucose fluid on incidence of perioperative hypoglycemia and hemodynamic

Authors: Olajumoke T.O, Afolayan J.M, Raji S.A, Ojo K.O

 DOI: https://dx.doi.org/10.18535/jmscr/v8i9.03

Abstract

Aim: This study aimed at finding the effect of preoperative fasting and preoperative glucose oral fluid on perioperative hypoglycemia and haemodynamics.

Methods: Seventy patients of class 1 and 2 ASA status within 2 and 10 years of age were recruited and randomly divided into two groups of thirty five (35) patients each. Group I patients were kept nil per oral from midnight and Group II patients were given clear glucose (2mls per kilogramme) fluid 2 hours prior to the surgery. All surgeries were done under general anaesthesia plus minus endotracheal intubation with standard monitoring. Standard anaesthesia technique was followed for all the patients. Samples were taken for random blood sugar were taken prior to. and immediately after induction of anaesthesia then at 30mins, an hour and 2hours after. The vital signs were taken. baseline before induction and after induction of anaesthesia every 15mins during the surgery and after surgery. The vital signs preoperatively, at induction and at 30mins, an hour and two hours were analyzed.

Result: The average blood glucose was lower in group A (< 50mg/dl level of hypoglycemia set for this study) when compared to group B. Group A developed more hypoglycaemia and tachycardia while patients who had fluid intake 2hrs prior to surgery did not develop hypoglycaemia and have better haemodynamics.

Keywords: children, blood glucose, preoperative, fasting, hypoglycemia.

References

  1. American Society of Anesthesiologists: Practice guidelines for preoperative fasting and the use of pharmacologic agents to reduce the risk of pulmonary aspiration: Application to healthy patients undergoing elective procedures–a report by the American Society of Anesthesiologists Task Force on Preoperative Fasting. ANESTHESIOLOGY 1999; 90:896–905.
  2. Bowie MD, Mulligan PB, Schwartz R. Intravenous glucose tolerance in the normal newborn infant the effects of a double dose of glucose and insulin. Pediatrics. 1963 Apr;31:590–5
  3. Pramod Gupta; Sehgal R, Journal of Anaesthesiology Clinical Pharmacology, 2004, 20(2), 161-163
  4. Robert H. Friesen, Anaesthesia and Analgesia, 2002, 95, 1572-1576.
  5. Bevan JC; Mary C. Burn, British Journal of Anaesthesia, 1973, 45:115s
  6. Jensen BH; Wernberg M, British Journal of Anaesthesia, 1982, 54:1071
  7. Vander Walt JH and Carter JA, Anaesthesia and Intensive care, 1986, 14,352-359.
  8. Nancy Redfern; Addison GM, Anaesthesia, 1986, 41,272-275.
  9. Diaz JH, Journal of Paediatric surgery, 1985, 20,502-507.

Corresponding Author

Dr Olajumoke T.O

Department of Anaesthesia and Intensive Carem, LAUTECH Teaching Hospital, Osogbo, Osun State