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Category: Volume 08 Issue 08 August 2020
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Title: Platelet Indices in small for gestational age term newborns

Authors: Dr Priti Saini, Dr Rinku Saini, Dr Lovesh Saini, Dr Yashvi Gehlot

 DOI: https://dx.doi.org/10.18535/jmscr/v8i8.56

Abstract

Background & Objectives: Our study aimed to compare the Platelet Indices in full term small for gestational age newborns as compared to full term appropriate for gestational age newborns.

Materials and Methods: We included 30 term small for gestational age newborns as cases and 30 term appropriate for gestational age newborns as controls. Platelet Indices (Total Platelet Count [TPC], Mean Platelet Volume [MPV], Platelet Distribution Width [PDW], Plateletcrit [PCT], Platelet Large Cell Ratio [PLCR] ) were estimated in samples taken on LD 1-3 of the cases and controls.

Results: Small for gestational age newborns showed a decreased Total Platelet count [TPC] (p 0.412) and Plateletcrit [PCT] (p 0.566) as compared to the controls. Mean Platelet Volume (MPV), Platelet distribution width (PDW) and Platelet large cell ratio (PLCR) were increased in small for gestational age term newborns as compared to the controls; with p values of 0.592, 0,045 and 0.269 respectively. The increase in PDW (Platelet distribution width) was found to be statistically significant.

Interpretations & Conclusions: Small for gestational age term newborns have many hemostatic abnormalities as compared to appropriate for gestational age term newborns. The estimation of Platelet indices might help in predicting the risk, severity of bleeding complications in such newborns and help in their timely management.

Keywords: hemostatic, gestational, indices.

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Corresponding Author

Dr Rinku Saini

MD Pediatrics, Associate Professor, Pediatric Medicine, SMS Medical College, Jaipur, Rajasthan