Details
Category: Volume 08 Issue 08 August 2020
Hits: 906

Title: To study bacteriological and antibiotic susceptibility profile of burn wound isolates in a tertiary care centre in JAMMU

Authors: Dr Perika, Dr Shashi Sudhan Sharma, Dr Priyanka Sharma

 DOI: https://dx.doi.org/10.18535/jmscr/v8i8.48

Abstract

Burn wounds are one of the most common and devastating form of trauma. Infections are an important cause of morbidity and mortality in burn patients. This was a retrospective study conducted in Microbiology department of GMC JAMMU over a span of 6 months [JAN 2018- JUNE 2018]. Samples transported to microbiology laboratory were immediately processed and antibiotic sensitivity was performed according to standard laboratory procedures (CLSI guidelines).   Total of 101 samples were taken from 101 patients admitted in burn ward. Records of these swabs taken from burn wound patients were analysed. The most frequent isolates were Pseudomonas aeruginosa, Klebsiella pneumoniae, Staphylococcus aureus, Proteus. Antimicrobial sensitivity showed Imipenem was most effective drug among Gram negatives and Linezolid was most effective against Gram positive isolates. It is very crucial for every burn unit to determine specific pattern of burn wound colonization and antimicrobial susceptibility pattern. This will enable early treatment of imminent septic episodes with proper empirical systemic antibiotics thus improving overall infection  related  morbidity and mortality.

References

  1. Megha Priyadarshini, Manoj Kumar, Ashok Kumar Sharma, Amber Prashad, Kumari Seema. Bacteriological Profile and Antibiogram of Burn Wound Infections from Burn Patients at RIMS, Ranchi. Int J Med Res Prof. 2018 Nov; 4(6):203-06.
  2. World Health Organization. 2017. Burns (online). Available from http://www.who.int/mediacentre/factsheets/fs365/en/; accessed 2Jun. 2017.
  3. Peng DZ1, Liu XL, Liu ZY, Shu WT, Zhou X, Liu J, et al. Analysis of distribution characteristics and drug resistence of 2748 strains of pathogens isolated from burn patients.
  4. V G Bhat & S D Vasaikar (2010) Bacteriological profile and antibiogram of aerobic burn wound isolates in Mthatha, Eastern Cape, South Africa, Southern African Journal of Epidemiology and Infection, 25:4, 16-19.
  5. Erol S, Altoparlak U, Akcay MN, Celebi F, Parlak M. Changes of microbial flora and wound colonization in burned patients. Burns 2004; 30: 357-61.
  6. Datta S, Ghosh T, Sarkar D, Tudu NK, Chatterjee TK, Jana A. Bacteriological Profile of Burn Wounds and Their Antibiotic Susceptibility Pattern in a Tertiary Care Hospital. Int J Sci Stud 2016;4(5):141-45.
  7. Chiller K, Selkin BA, Murakawa GJ. Skin microflora and bacterial infections of the skin. J Investig Dermatol Symp Proc 2001;6:170–4.
  8. Avni, A. Levcovich, D.D. Ad-El, L. Leibovici, M. Paul, Prophylactic antibiotics for burns patients: systematic review and meta-analysis, Bmj 340 (2010 Jan 1)c241.
  9. Srinivasan, A.M. Vartak, A. Patil, J. Saldanha, Bacteriology of the burn wound at the BaiJerbai Wadia hospital for children, Mumbai, India—a 13-year study, PartI Bacteriological profile, Indian J. Plast. Surg. 42 (2) (2009 Jul) 213, official publication of the Association of Plastic Surgeons of India.
  10. Gupta M, Naik AK, Singh SK. Bacteriological profile and antimicrobial resistance patterns of burn wound infections in a tertiary care hospital. Heliyon 5 2019; e02956 .
  11. Dash, P. Mishra, S. Routray, Bacteriological profile and antibiogram of aerobic burn wound isolates in a tertiary care hospital, Odisha, India, Int. J. Med. Med. Sci. 3 (2013) 460–463.
  12. P. Singh, R. Goyal, V. Manchanda, S. Das, I. Kaur, V. Talwar, Changing trends in bacteriology of burns in the burns unit, Delhi, India, Mol. Biol. Rep. 29 (2003) 129–133.
  13. C. Ozumba, B.C. Jiburum, Bacteriology of burn wounds in Enugu, Nigeria, Burns 26 (2000) 178–180.
  14. Guggenheim, R. Zbinden, A.E. Handschin, A. Gohritz, M.A. Altintas, P. Giovanoli, Changes in bacterial isolates from burn wounds and their antibiograms: a 20-year study (1986-2005), Burns 35 (2009) 553–560.
  15. Pujji OJ, Nakarmi KK, Shrestha B, Rai SM, Jeffery SL. The Bacteriological Profile of Burn Wound Infections at a Tertiary Burns Center in Nepal. J Burn Care Res 2019; 40(6):838-845.

Corresponding Author

Dr Shashi S Sharma

Professor, PI and Nodal Officer, Dept. of Microbiology, GMC Jammu, India