Title: Etiology of Pancytopenia in a Study in a Tertiary Care Hospital in North Andhra
Authors: Dr S.Sreenivas, Dr Marri Lakshmi Harika, Dr Tati Hyma, Dr Gadipudi Mounika
DOI: https://dx.doi.org/10.18535/jmscr/v8i8.45
Abstract
Background: pancytopenia is defined as the simultaneous existence of anemia, leukopenia, thrombocytopenia. It is encountered in day to day clinical practice. Knowing the underlying cause determines the appropriate management. The aim of the study was to obtain the common causes causing pancytopenia in patients admitted in tertiary care hospital in north Andhra and the frequency of various etiological factors.
Materials and Methods: This prospective observational study was done in the department of general medicine in tertiary hospital over 7 months period from January 2020 to July 2020. History, blood investigations, the peripheral smear was done for all patients and bone marrow examination was done for selected patients.
Results: out of 100 patients 61 were male and 39 were female. Megaloblastic anemia was the commonest cause that was observed followed by aplastic anemia, chronic liver disease, haematological malignancy, infections like HIV and malaria, SLE.
Conclusion: The most common cause of pancytopenia in this part of India is megaloblastic anemia which is a curable deficiency.
Keywords: pancytopenia, megaloblastic anemia, aplastic anemia.
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