Title: A Novel Approach to Managing Haemorrhage in Dengue Haemorrhagic Fever– A Life Saved!
Authors: Dr Pai Ashutosh A., Dr Sutay Nita R., Dr Kapari Karan
DOI: https://dx.doi.org/10.18535/jmscr/v8i8.24
Abstract
Dengue fever is one of the most commonly encountered mosquito-borne viral infections in India. It can present with a diverse clinical spectrum ranging from a simple undifferentiated fever to Dengue Haemorrhagic Fever with Multiorgan failure. Bleeding is responsible for a significant proportion of fatal outcomes in Dengue fever. We report this 10 year old female child with history of fever, bloody vomitus and passage of black coloured stools. On examination, child was Febrile with signs of Hypotensive shock, petechiae, hepatomegaly, jaundice, ascites and pedaloedema. Blood investigations revealed Dengue NS1 positive with thrombocytopenia, Hepatitis and abnormal coagulopathy. She was treated for shock with crystalloids and inotropes. Despite repeated transfusions of Fresh Frozen Plasma, Platelets and Packed Cells as recommended in guidelines, child continued to show bleeding. The Child was eventually put on Ventilator for worsening respiratory distress. Child was given a trial of Injection Octreotide infusion which was successful in stopping the bleeding, never before tried. Eventually child recovered and was discharged.
Keywords: octreotide; dengue; novel; bleeding.
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