Title: Does choice of mechanical prosthetic valve affect change in left ventricular functions after aortic valve replacement

Authors: Hakeem Zubair Ashraf, Nadeem-ul-Nazeer, Abdul Gani Ahangar, Farooq A Ganie, Mohammad, Yaqoob Khan, Haroon Rashid Naqshi, Abdul Majeed Dar, Mohammad Akbar Bhat, Syed Mohsin, Peerzada Hidayat, Pradeep Kumar, Rouf Gul

 DOI: https://dx.doi.org/10.18535/jmscr/v8i6.04

Abstract

 

Background: We sought to determine whether the choice of mechanical prosthetic valve (Bileaflet or Monoleaflet) has any effect on change in left ventricular functions and valve gradients after aortic valve replacement (AVR) in patients  with  pure  aortic valve  disease.

Methods: Eighty two patients were  included  in  the  study  who underwent  aortic  valve  replacement  for  isolated  aortic  valve disease using either a bileaflet (Group1)  or a monoleaflet  valve (Group 2). The  measurements included Left Ventricular End-Diastolic (LVEDd) and Left Ventricular End-Systolic (LVEDs) dimensions and Left Ventricular End-Diastolic (LVEDV) and Left Ventricular End-Systolic (LVESV) volumes, Ejection  Fraction (EF), Stroke Volume (SV), NYHA class  and  Cardiac Output (CO). Comparisons of  different parameters  were  made in two groups to  determine  the  significance  of  choice  of  prosthetic  valve.

Results: Aortic valve replacement induces a favourable remodeling of the left ventricle and a significant improvement in left ventricular functions. There was no statistically significant difference in the measured parameters between the two groups and hence choice of prosthetic valve does not influence the outcome.

Conclusion: Impaired cardiac functions show significant improvement after AVR. Functional class was improved or maintained in all the patients in both the groups. Left ventricular systolic pump functions were improved in almost all the patients, comparable in both the groups.

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Corresponding Author

Dr Hakeem Zubair Ashraf (MCh.)

Department of CVTS, Sher-i-Kashmir Institute of Medical Sciences (SKIMS) Soura, Srinagar, Kashmir, India, 190011