Title: Kikuchi disease: A Case Report from Himachal Pradesh
Authors: Lekshmi Vijayamohanan, Sarita Asotra, Pooja Murgai, Roop Preet Kaur, Ankita Sharma
DOI: https://dx.doi.org/10.18535/jmscr/v8i3.113
Abstract
Kikuchi disease is a self limiting, benign disorder with predominantly supportive therapy, it’s important to accurately diagnose with histopathology playing the key role; in order to provide the best patient care and avoid wrongful treatment. We present a case of a young female presenting with matted cervical lymph nodes, in Himachal Pradesh, India which turned out to be Kikuchi Fujimoto disease on lymph node biopsy; despite a clinical suspicion of Tuberculosis.
Keywords: Kikuchi Fujimoto disease, lymph nodes, matted, tuberculosis, necrosis.
References
- Kikuchi M. Lymphadenitis showing focal reticulum cell hyperplasia. Nippon Ketsueki Gakkai Zasshi. 1972;35:378–80.
- Fujimoto Y, Kozima Y, Yamaguchi K. Cervical subacute necrotizing lymphadenitis. A new clinicopathological agent. Naika. 1972; 20:920–7.
- Ramirez AL, Johnson J, Murr AH. Kikuchi-Fujimoto’s disease: an easily misdiagnosed clinical entity. Otolaryngol Head Neck Surg. 2001;125:651– 3.
- Perry AM, Choi SM. Kikuchi-Fujimoto disease: A review. Arch Pathol Lab Med. 2018; 142:1341–6.
- Xu S, Sun W, Liu J. Kikuchi-Fujimoto disease: a case report and the evaluation of diagnostic procedures. BMC Oral Health. 2019 Oct 21;19(1): 223. doi: 10.1186/s12903-019-0920-4. PMID: 31638953; PMCID: PMC6805530.
- Mathew LG, Cherian T, Srivastava VM, Raghupathy P. Histiocytic necrotizing lymphadenitis (Kikuchi's disease) with aseptic meningitis. Indian Pediatr 1998;35:775-7.
- Hutchinson CB, Wang E. Kikuchi-Fujimoto disease. Arch Pathol Lab Med 2010;134: 289-93.
- Kuo TT (1995) Kikuchi’s disease (histiocytic necrotizing lymphadenitis). A clinicopathologic study of 79 cases with an analysis of histologic subtypes, immunohistology, and DNA ploidy. Am J Surg Pathol 19: 798-809.
- Bosch X, Guilabert A, Miquel R, Campo E. Enigmatic Kikuchi-Fujimoto disease: A comprehensive review. Am J Clin Pathol 2004;122:141-52.
- Pilichowska ME, Pinkus JL, Pinkus GS. Histiocytic necrotizing lymphadenitis (Kikuchi-Fujimoto disease): Lesional cells exhibit an immature dendritic cell phenotype. Am J Clin Pathol 2009;131:174-82.
- Chaitanya BN, Sindura C. Kikuchi's disease. J Oral Maxillofac Pathol 2010;14:6-9.
- Kwon SY, Kim TK, Kim YS, Lee KY, Lee NJ, Seol HY. CT findings in Kikuchi disease: Analysis of 96 cases. AJNR Am J Neuroradiol 2004;25:1099-102.
- Seong GM, Kim JH, Lim GC, Kim J. Clinicopathological review of immunohistochemically defined Kikuchi- Fujimoto disease-including some interesting cases. Clin Rheumatol 2012;31:1463-9.
- Mahajan T, Merriman RC, Stone MJ. Kikuchi-Fujimoto disease (histiocytic necrotizing lymphadenitis): Report of a case with other autoimmune manifestations. Proc (Bayl Univ Med Cent) 2007;20:149-51.