Title: A comparative study of carotid artery intima media thickness in hypertensive smokers and non hypertensive smokers

Authors: Dr Aditya Jain, Dr Ajay Pal Singh

 DOI: https://dx.doi.org/10.18535/jmscr/v8i3.42

Abstract

   

Introduction: Cardiovascular disease is the leading cause of death globally. In 2017-18, Non communicable diseases led to 38 million (68%) deaths out of a total of 56 million deaths worldwide. India is currently in the midst of this global Cardiovascular Disease epidemic.

Method: Case control study

Aim of the Study: To compare carotid artery intima-media thickness(cIMT) in Hypertensive smokers and smokers without Hypertension.

Result: In this study mean value of cIMT was found to be significant (P < 0.05) as mean of Case group (0.970) is significantly higher than that of Control group (0.735). Mean cIMT was highest in the study group i.e 1.114 mm in the population of age above 70 years, similarly Mean cIMT was highest in the control group i.e. 0.821mm in the population of age above 60 years.

Conclusion: The present study and its observations  makes it imminent that Hypertension affects every cIMT measurement of the study subjects. cIMT measurement has as positive correlation with the increasing age.

Keywords: Hypertension, cIMT, Cardiovascular disease.

References

  1. Stein JH, Fraizer MC, Aeschlimann SE, Nelson-Worel J, McBride PE, Douglas PS. Vascular age: integrating carotid intima-media thickness measurements with global coronary risk assessment. Clin Cardiol 2004;27:388–392.
  2. Gepner AD, Keevil JG, Wyman RA, Korcarz CE, Aeschlimann SE, Busse KL, Stein JH. Use of carotid intima-media thickness and vascular age to modify cardiovascular risk prediction. J Am Soc Echocardiogr 2006;19:1170–1174.
  3. Touboul PJ, Hennericim G, Meairs S. Mannheirn intima- media thickness consensus.Cerebrovasc Dis 2004; 18(4): 346-7.
  4. Ebrahim S, Papacosta O, Whincup P, Wannamethee G, Walker M, Nicolaides AN, Dhanjil S, Griffin M, Belcaro G, Rumley A, Lowe GD.Carotid plaque, intima media thickness, cardiovascular risk factors, and prevalent cardiovascular disease in men and women: the British Regional Heart Study.1999 Apr;30(4):841-50.
  5. J Ahmad et al. Inflammatory Markers, Insulin Resistance and Carotid Intima-MediaThickness in North-Indian Type 2 Diabetic Subjects. Japi • vol. 55 october 2007
  6. Hamma S et al , (Stroke 2001 April; 32(4) : 830-5.
  7. Sahoo, Ratnakar & Krishna, M & Subrahmaniyan, D & Dutta, Tarun & Elangovan, S. (2009). Common carotid intima-media thickness in acute ischemic stroke: A case control study. Neurology India. 57. 627-30. 10.4103/0028-3886.57822.
  8. Łoboz-Rudnicka M, Jaroch J, Bociąga Z, Rzyczkowska B, Uchmanowicz I, Polański J, Dudek K, Szuba A, Łoboz-Grudzień K. Impact of cardiovascular risk factors on carotid intima-media thickness: sex differences.Clin Interv Aging.2016 May 23;11:721-31. doi: 10.2147/CIA.S103521. eCollection 2016.
  9. Mohamed M. Elrakhawy, Azza A. El-Baiomy, and Mervat M. El-Eshmawy Carotid Intima Media Thickness Is Independently Associated with Male Gender, Middle Age, and IGF-1 in Metabolically Healthy Obese Individuals Volume 2014 Article ID 545804 7 pages| https://doi.org/10.1155/2014/545804.
  10. Magnussen CG. Carotid artery intima-media thickness and hypertensive heart disease: a short review. Clin Hypertens. 2017;23:7. Published 2017 Apr 2. doi:10.1186/s40885-017-0063-3

Corresponding Author

Dr Aditya Jain

P.G. Student, Department of Medicine, Gajra Raja Medical College, Gwalior (M.P.), India