Title: A Study on Histomorphological Patterns of Thyroid Lesions – An Experience of a Rural Tertiary Care Centre

Authors: K. Prathipa, P.S. Vamitha

 DOI: https://dx.doi.org/10.18535/jmscr/v8i1.154

Abstract

Objective: Thyroid lesions are the most common endocrine problem encountered in routine clinical practice. This study describes the various spectrums of thyroid lesions in surgically resected specimen and its correlation with age, gender and cytological findings.
Materials and Methods: A retrospective study of thyroid lesions were conducted in the Department of pathology in a rural tertiary care centre over a period of 1 year from Jan 2018 to Dec 2018. Totally 145 cases were studied which include 109 non neoplastic, 7 benign and 29 malignant cases. Histopathological findings and its correlation with various parameters were evaluated.
Results: Totally 145 surgically resected thyroid specimens were received during the study period of one year with a female: male ratio of 10.7: 1. The age group ranges from 14 years to 67 years and peak incidence was noted in 31-40 years group. Most common lesion noted was nodular goiter (54%) followed by thyroid malignancies (20%). Other lesions observed were thyroiditis (14%), follicular adenoma (5%), nodular hyperplasia with thyroiditis (6%) and toxic goiter (1%). Among the malignant tumours, the predominant lesion was papillary carcinoma (90%) followed by follicular (7%) and medullary carcinoma (3%).
Conclusion: Non neoplastic lesions are more common than neoplastic lesions with a striking female predominance. This study shows increased prevalence of thyroid lesions with a rising incidence of papillary carcinoma thyroid among the middle aged individuals especially males.
Keywords: thyroid lesions, FNAC, papillary carcinoma, goitre

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Corresponding Author

Dr K.Prathipa

Assistant Professor, Department of Pathology, Chengalpattu Medical College, Tamil Nadu, India