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Category: Volume 08 Issue 01 January 2020
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Title: To study the prevalence of Gastroesophageal reflux disease in patients with airway obstructive disease

Authors: Dr Ashutosh Baheti, Dr J S Namdhari, Prof. Dr Sushma Trikha, Prof. Dr O P Jatav, Prof. Archana Kansal, Dr Neelima Singh

 DOI: https://dx.doi.org/10.18535/jmscr/v8i1.142

Abstract

Introduction

Obstructive airway diseases (OAD) is a major cause of chronic morbidity and mortality throughout the world; it is the fourth leading cause of death in the world(2). OAD is a preventable and treatable disease with some significant extra pulmonary effects that may contribute to the severity in individual patients. Its pulmonary component is characterized by airflow limitation that is not fully reversible. The airflow limitation is usually progressive and associated with an abnormal inflammatory response of the lung to noxious particles and gases(1).Gastro esophageal reflux disease (GERD) is the collective term used to describe abnormal reflux of gastric content into the esophagus as well as the symptoms and mucosal disease associated with it. Clinical manifestations of GERD include heart burn, regurgitation, dysphagia, chest pain, cough and other esophageal symptoms. GERD is known to cause errosive esophagitis and Barrette esophagus. Currently upper GIT endoscopy is the main clinical tool for visualizing esophageal lesions(3).

Micro aspiration of gastric contents and/or vagal nerve induced bronchospasm from gastric acid irritation of the esophagus may contribute to the observed association between GERD and pulmonary disease or symptoms(4).

Gastroesophageal reflux disease (GERD) may cause, trigger, or exacerbate many pulmonary diseases. The physiologic link between GERD and pulmonary diseases has been extensively studied in asthma; however, in other pulmonary diseases, including interstitial pulmonary fibrosis (IPF), cystic fibrosis and OAD, the link has been less well studied(5).

The prevalence of reflux symptoms is related to the degree of obstruction of airflow in patients with OAD(6).

References

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Corresponding Author

Dr J S Namdhari

Assistant Professor, Department of Medicine GRMC Gwalior, Madhya Pradesh, India