Title: Morbidity and Mortality Profile of Newborns Admitted to the Neonatal Intensive Care Unit of a Tertiary Care Teaching Hospital of Assam

Authors: Anupama Deka, Bidyut Bhusan Nath, Anjana T Nair

 DOI: https://dx.doi.org/10.18535/jmscr/v8i1.109

Abstract

Introduction:  India contributes to one-fifth of global live births and more than a quarter of neonatal deaths[1]. Neonatal mortality is one of the very important indicators, which reflect a country’s development. It is of utmost importance to analyse the spectrum of neonatal diseases and the causes of mortality, which in turn will help in formulating strategies for control of neonatal mortality.                  

Objective: To study the morbidity and mortality profile of neonates admitted in Neonatal Intensive Care Unit (NICU).

Methodology: A retrospective observational study was done in the Neonatal Intensive Care Unit (NICU) to identify the main causes of neonatal morbidity and mortality of admitted neonates over a period of three years from January 2016 to December 2018.

Results: A total of 11,654 neonates were admitted in the NICU during the study period, 60.5% were in the Inborn and 39.5% were in the Outborn. 47.7% of total admissions in our NICU were LBW. The major causes of admission to NICU were observed to be jaundice, RDS, sepsis, Birth asphyxia and Meconium aspiration syndrome. NICU mortality during the study period was found to be 12.37%. Birth asphyxia, sepsis, RDS and MAS were found to be the main contributors of mortality in our NICU.

Conclusion: This study identifies Birth asphyxia as the most important cause of mortality. Outcomes of this study can be utilized in planning and modifying existing health care services for improved care of the newborn.

Keywords: NICU, Morbidity, Mortality, Birth asphyxia

References

  1. State of newborn health in India. Journal of Perinatology (2016) 36, S3–S8
  2. WHO Global Health Observatory Data Repository, Available at : http://www.who.int/gho/database/en/(Accessed : 10th November 2019.
  3. Bhutta ZA, Das JK, Bahl R, Lawn JE, Salam RA, Paul VK, et al. Can available interventions end preventable deaths in mothers, newborn babies, and stillbirths, and at what cost? Lancet. 2014;384:347-70. Medline: 24853604 doi:10.1016/S0140-6736 (14)60792-3
  4. Liu L, Oza S, Hogan D, Perin J, Rudan I, Lawn JE et al. Global, regional, and national causes of child mortality in 2000–13, with projections to inform post-2015 priorities: an updated systematic analysis. Lancet 2015; 385(9966): 430–440.Medline:25280870 doi:10.1016/S0140-6736(14)61698-6)
  5. Jain S, Bhakoo ON, Singh M (1990) Neonatal Monitoring, Recommendations and Proceedings of theSeminar 1990. Chathram Hospital & Research Centre. Indore, pp: 6-17
  6. Martins Christine, Barcelon Ariane, Lima Fernanda, Gaíva Maria.(2014). ‘Profile of Morbidity and Mortality in at risk Newborns’. Cogitare Enfermagem.19.109-115.
  7. Chan MCK. ‘Specific problems in developing countries’. In: Rennie JM, Roberton NRC (editors). Textbook of Neonatology. (3rd edition. Edinburgh: Churchill Livingtone 2000); 111-18
  8. Bora JK, Saikia N.(2018) ‘Neonatal and under-five mortality rate in Indian districts with reference to Sustainable Development Goal 3: An analysis of the National Family Health Survey of India (NFHS),’ 2015–2016.PLOS ONE 13(7): e0201125.
  9. Kumar R, Mundhra R, Jain A, Jain S. ‘Morbidity and mortality profile of neonates admitted in special newborn care unit of a teaching hospital in Uttarakhand, India’. Int J Res Med Sci(2019);7:241-6
  10. Sharma AK, Gaur A. ‘Profile of neonatal mortality in special newborn care unit of tertiary care hospital’. Int J Contemp Pediatr(2019);6
  11. Malik S, Gohiya P, Khan IA. ‘Morbidity profile and mortality of neonates admitted in Neonatal Intensive Care Unit of a Central India Teaching Institute: A prospective observational study’. J ClinNeonatol (2016); 5:168-73.
  12. Modi R, Modi B, Patl JK, Punitha KM. ‘Study of the Morbidity and the Mortality Pattern in the Nonatal Intensive Care Unit at a Tertiary Care teaching Hospital in Gandhinagar District, Gujarat, India’. J Res Med Den Sci 3:208-(2015);12. DOI: 10.5455/jrmds.20153311
  13. Kumar MK, Thakur SN, Singh BB. ‘Study of the Morbidity and the Mortality Patterns in the Neonatal Intensive Care Unit at a Tertiary Care Teaching Hospital in Rohtas District, Bihar, India’. J Clin Diagn Res (2012);6:282-5. DOI: JCDR/3687:1994
  14. Harsha PJ, Iyer CR, Rathod AD, Nagendra K, Chandan CK, Gornale VK. ‘A Prospective observational study of short term morbidity pattern in preterm newborns delivered in a tertiary care hospital’. J Evidence based Med Healthcare (2015); 2:5432-37. DOI: 10.18410/ jebmh/2015/755
  15. Baruah MN, Panyang PP. ‘Morbidity and Mortality Profi le of Newborns Admitted to the Special Care Newborn Unit ( SCNU ) of A Teaching Hospital of Upper Assam, India – A Three Year Study’. J Med SciClin Res (2016);4:11689-95. DOI: 10.18535/jmscr
  16. Sonia Bhatt, Abhishek Singh, Shewtank Goel, Anil Kumar Goel. ‘An Evaluation of mortality pattern in the Neonatal Intensive Unit of a tertiary care centre from Western Uttar Pradesh’. J. App. Med. Sci., June (2016); 4(6E):2224-2228
  17. Niru Prabha Saharia, Arati Deka, Vivekananda M.S ‘Mortality and Morbidity Pattern of Neonatal ICU of Gauhati Medical College and Hospital’. IOSR Journal of Dental and Medical Sciences(2016) vol 15, issue 6, PP 73-75.
  18. Kannan R, Rao S, Mithra P, Rajesh SM, Unnikrishnana B, Rekha T. ‘Neonatal Mortality and Morbidity in a Tertiary Care Hospital of Coastal South India’. J Nepal Paediatr Soc(2017);37(3):232-237
  19. Rakholia R, Rawat V, Bano M, Singh G. ‘Neonatal morbidity and mortality of sick newborns admitted in a teaching hospital of Uttarakhand’. CHRISMED J Health Res. (2014) Oct 1;1(4):22
  20. Sridhar PV, Thammanna PS, Sandeep M. ‘Morbidity Pattern and Hospital Outcome of Neonates Admitted in a Tertiary Care Teaching Hospital, Mandya’. Int J Sci Stud(2015);3(6):126-129.
  21. Panda S. Mortality & morbidity profi le in vlbw & elbw neonates admitted to NICU in HMCH. Yuva J Med Sci(2016);1:51-5.
  22. Aggarwal KC, Gupta R, Sharma S, Sehgal R, Roy MP. Mortality in newborns referred to tertiary hospital: Anintrospection. J Family Med Prim Care.(2015);4(3):435-438

Corresponding Author

Anjana T Nair

Department of Pediatrics, Silchar Medical College and Hospital, Silchar, Assam, India