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Category: Volume 08 Issue 01 January 2020
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Title: A study on mean blood platelet volume levels in patients with depression and generalized anxiety disorder

Authors: Dr Lakshimi Borgohain, Dr Monalisa Boro

 DOI: https://dx.doi.org/10.18535/jmscr/v8i1.103

Abstract

Background: Stressful events, depression and anxiety usually elevate circulating levels of blood catecholamines which causes an increase in platelet activity and sympathoadrenal activation is thought to stimulate platelet through the α -2 receptors resulting in an increase in platelet volume.

Aim: To estimate the mean blood platelet volume levels in depressive disorder and generalized anxiety disorder patients.

Methods: The study was a hospital based cross sectional study conducted in the Department of Psychiatry, Assam Medical College and Hospital, Dibrugarh, Assam during the time period of June 2018 to May 2019 (1 year) after obtaining ethical clearance from the Institution Ethics Committee.

Results: Mean MPV level of Depression cases (13.25 ± 1.31 fl) was higher than GAD cases (11.79 ± 1.71 fl). It was statistically found to be significant (p value <0.001).

Conclusion: To the best of our knowledge no study till date studied the interrelationship among MPV, severity of Depression and GAD.

Keywords: Depression, generalized anxiety disorder, mean blood platelet volume.

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Corresponding Author

Dr Monalisa Boro

Post Graduate Trainee, Department of Psychiatry, Assam Medical College and Hospital, Dibrugarh, Assam