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Category: Volume 08 Issue 01 January 2020
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Title: Correlation of morphological profile and receptor status in breast carcinoma: An institutional study in tertiary care hospital

Authors: Dr Anup Kumar, Dr Deergha Singh, Dr M.L.Gupta

 DOI: https://dx.doi.org/10.18535/jmscr/v8i1.86

Abstract

Background:  Receptor status assessment is not routinely carried out in patients of breast cancer in the Indian subcontinent. Limited data is available on histological and receptor status in Indian patients. In this study receptor status has been correlated with morphological prognostic parameters.

Objective: To analyze receptor status and its correlation with morphological prognostic parameters in Indian females.

Methods:  50 mastectomy specimens of breast carcinoma were received in the department of pathology at Geetanjali medical college and hospital, Udaipur, Rajasthan, India. All the 50 cases were subjected for ER, PR, HER 2 Neu receptor study.

Result: 64% patients diagnosed with breast cancer were 50 years or younger in age. 94% patients were diagnosed as Invasive ductal carcinoma whereas 6 % patients were diagnosed with tubular and tubulobular carcinoma. Only 4% cases were ER/ PR/ HER 2 Neu positive and 16% cases were triple negative indicating poor prognosis.

Keywords: Breast cancer, Invasive ductal carcinoma (IDC), Estrogen Receptor, Progesterone Receptor, Her 2 Neu Receptor.

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Corresponding Author

Dr Anup Kumar

Department of Pathology, RDBP Jaipuria Hospital, Jaipur, Rajasthan, India