Title: Efficacy of Rifaximin in patients with Irritable Bowel Syndrome and its Comparison with Previous Drugs: A Retrospective Study
Authors: Sangeeta Yadav , Omkar Singh, Manoj Kumar, Ashish Gautam
DOI: https://dx.doi.org/10.18535/jmscr/v8i1.74
Abstract
Irritable bowel syndrome often becomes a headache for the patient as well as doctor and till date no drug has proven to be 100% effective in managing these patients. We studied Rifaximin, one of the latest drug for the management of this disorder and compared it with drugs previously used. This study, a combination of retrospective as well as prospective showed that Rifaximin has the most satisfactory results in these patients, however the results were not sustained as with other drugs.
References
- Schmulson MW, Chang L (1999). "Diagnostic approach to the patient with irritable bowel syndrome". J. Med.107(5A): 20S–26S. doi:10.1016/S0002-9343(99)00278-8.PMID 10588169.
- Malagelada, JR (2006). "A symptom-based approach to making a positive diagnosis of irritable bowel syndrome with constipation". International journal of clinical practice60(1): 57–63. doi:1111/j.1368-5031.2005.00744.x.PMID 16409429.
- Paré P, Gray J, Lam S et al. (2006). "Health-related quality of life, work productivity, and health care resource utilization of subjects with irritable bowel syndrome: baseline results from LOGIC (Longitudinal Outcomes Study of Gastrointestinal Symptoms in Canada), a naturalistic study". Clinical therapeutics 28 (10): 1726–35; discussion 1710–1. doi:1016/j.clinthera.2006.10.010.PMID17157129.
- Maxion-Bergemann S, Thielecke F, Abel F, Bergemann R (2006). "Costs of irritable bowel syndrome in the UK and US". PharmacoEconomics24 (1): 21–37.doi:2165/00019053-200624010-00002.PMID 16445300.
- "IBS and Depression Connection and Treatments". Webmd.com. Retrieved 2012-10-21.
- Thabane M, Kottachchi DT, Marshall JK (2007)."Systematic review and meta-analysis: The incidence and prognosis of post-infectious irritable bowel syndrome". Aliment Pharmacol Ther26 (4): 535–44. doi:1111/j.1365-2036.2007.03399.x. PMID 17661757.
- Vorous, Heather Van (19uu).Eating for I.B.S. Marlowe & Co..: Marlow & Co. ISBN 1569246009.
- Miller, V; Hopkins, L; Whorwell, PJ (2004 Dec). "Suicidal ideation in patients with irritable bowel syndrome.".Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2 (12): 1064–8. PMID 15625650.
- Spiegel, B; Schoenfeld, P; Naliboff, B (2007 Jul 15). "Systematic review: the prevalence of suicidal behaviour in patients with chronic abdominal pain and irritable bowelsyndrome.".Alimentary pharmacology & therapeutics 26 (2): 183–93. PMID 17593064.
- Holten KB, Wetherington A, Bankston L (2003)."Diagnosing the patient with abdominal pain and altered bowel habits: is it irritable bowel syndrome?".Am Fam Physician 67 (10): 2157–62. PMID 12776965
- DuPont HL, Jiang ZD, Okhuysen PC. A randomized, double-blind, placebo-controlled trial of rifaximin to prevent travelers’ diarrhea. Ann Intern Med. 2005 May 17, 142(10):805-12.
- Scarpellini E, Giorgio V, Gabrielli M, Filoni S, Vitale G, Tortora A, Ojetti V,Gigante G, Fundarò C, Gasbarrini A.Eur Rev Med Pharmacol Sci. 2013 May;17(10):1314-20.
- Jiang ZD, DuPont HL. Rifaximin: in vitro and in vivo antibacterial activity--a review. 2005;51 Suppl 1:67-72.
- Pimentel M, Lembo A, Chey WD, Zakko S, Ringel Y, Yu J, Mareya SM, Shaw AL, Bortey E, Forbes WP. N Engl J Med. 2011 Jan 6;364(1):22-32. doi: 10.1056/NEJMoa1004409.
- Schey R, Rao SS. Expert Rev Gastroenterol Hepatol. 2011 Aug;5(4):461-4. doi: 10.1586/egh.11.50.
- Lee SY, Kim JH, Sung IK, Park HS, Jin CJ, Choe WH, Kwon SY, Lee CH, Choi KW. Irritable bowel syndrome is more common in women regardless of the menstrual phase: a Rome II-based survey. J Korean Med Sci. 2007; 22(5):851–854. doi: 10.3346/jkms.2007.22.5.851.