Title: Role of Amniotic Membrane Transplantation in Brittle Cornea Syndrome-A Case Report

Authors: Dr Prasanta Kumar Nanda, Dr Subhrakali Paramguru

 DOI: https://dx.doi.org/10.18535/jmscr/v8i1.57

Abstract

To evaluate the efficacy of multilayer amniotic membrane transplantation with fibrin glue in sclera fragility and recurrent corneal ulceration in Brittle Cornea Syndrome. It is suggested that re-epithelialisation of a persistent epithelial defect in sclera and cornea is reduced by amniotic membrane transplantation in a patient of Brittle Cornea Syndrome leading to decrease in stromal inflammation and continued fibrosis, which is also aided by the combination of oxygenation and protection of the fragile epithelium by the amniotic membrane.

References

  1. Van herendeal BJ, Micro anatomy of human amniotic membrane
  2. Akle CA Immunogenesity of human amniotic epithelial cells after transfer into volunteers
  3. Ward DJ, Bennet JP,the long term results of use of human amnion in epithelial ulcers
  4. Faulk WP, Mathews RN Human amnion as an adjunctive to wound healing
  5. Trefold JD ,The amnion in surgery, past and present
  6. Shimazaki J,Tsubota K,Transplantation of AMG for patients with recurrent pterygium
  7. Tsuba K,Toda I,S aito H, Reconstruction of the corneal epithelium by AMT for severe ocular surface disorders.

Corresponding Author

Dr Subhrakali Paramguru

Post-Graduate Student, Dept. of Ophthalmology, SCM Medical College, Cuttack