Title: Study of Adverse Perinatal Events in full term small for Gestational age (SGA) Babies with or without Fetal Malnutrition

Authors: Dr Bapu Yelam M.D, Dr Saira Merchant M.D., Mrs. Jiji Yelam M.Sc.(Nursing), Dr Nilesh K.Tumram,M.D., Dr Abhishek Madhura M.D.

 DOI: https://dx.doi.org/10.18535/jmscr/v8i1.28

Abstract

Introduction

Fetal malnutrition (FM) is a risk factor for increased neonatal morbidities and mortalities worldwide. Clinicians challenge is to identify SGA babies whose health is endangered in utero because of a hostile intrauterine environment and to monitor and intervene appropriately[1].

This prospective observational study aim to know prevalence of fetal malnutrition in term SGA babies and to study occurrence of adverse perinatal events in term SGA babies with or without fetal malnutrition. Assessment of nutritional status of fetus has been a major concern to many clinicians because of the potentially serious sequelae of malnutrition on multiple organ systems[2,3]. Fetal biometry has been used to identify malnourished fetuses as early as possible. Perinatal problems and or long term central nervous system sequelae are known to occur primarily in babies with fetal malnutrition (FM) whether appropriate for gestational age (AGA) or SGA but  less so among those who are SGA but without fetal malnutrition[4]. There is a need for prompt identification of babies with FM. Features of malnutrition must therefore be sought for, and appropriately diagnosed and treated in every baby at risk. The anticipatory management of such infants at birth may decrease morbidity and improve the survival of such infants[4,5,6].  Study enrolled 903 term SGA neonates.CAN Score is applied and anthropometric evaluation is carried out between 24 to 48 hour of birth. Babies with adverse perinatal events are treated according to standard hospital protocol.

References

  1. WHO Chronicle 32:200-201,1978.
  2. Lockwood CJ and Weiner S.Assessment of fetal growth. Clin perinatol 13:2-35,1986.
  3. Georgieff MK and Sasanow SR. Nutritional assessment of the neonate. Clin Perinatol 13:72- 89, 1986
  4. Metcoff J. Clinical assessment of nutritional status at birth. Fetal malnutrition and SGA are not synonymous. Pediatr Clin North Am 41:875-91,1994.
  5. Jayant D and Rajkumar J. Study of the prevalence and high risk factors for fetal malnutritution in term newborn. Ann Trop Paediatr , 19:273-77,1999.
  6. Scott KK and Usher RH. Fetal malnutrition: Its incidence causes and effects .Am J Obstet Gynaecol 94: 951-63,1966.
  7. Van Wassenaer A. Neurodevelopmental consequences of being born SGA.Pediatr Endocrinol Rev 2:372-377,2005.
  8. Sankhyan N,Sharma VK,Singh S, Detection of fetal malnutrition using “CANSCORE”. Indian J.Pediatr.76:903-906,2009.
  9. Walter F.J. Ramaekers LHJ.The ponderal index as a measure of the nutritional status at birth and its relation to some aspects of neonatal morbidity.J Perinat Med.10:42-47,1982.
  10. Villar J ,Smeriglio V.Martorell R, Brown H, Klein RE. Heterogenous growth and mental development of IUGR infants during the first 3 years of life.Pediatrics 74:783-791,1984.
  11. Adair L, Popkin B. Birth weight, maturity and proportionality in Filipino infants. Hum Biol.60:319-339,1988.
  12. Kishan J, ElzoukiAY, Mir NA, Faquih AM.Ponderal index as predictor of neonatal morbidity in SGA .Ind J Pediatr.52:133-137,1985.
  13. Yagel S,Zacut D,Igelstein S,Palti Z, Huruitz A, Rosenn B.In utero ponderal index as a prognostic factor in the evaluation of intrauterine growth retardation. Am J Obstet Gynecal 157:415-419,1987.
  14. Jarai I.J. Mestyan K Schuktz A, Laxar M, H alasz I Krasy.Body size and neonatal hypoglycaemia in intrauterine growth retardation. Early Hum Dev1:25-38,1977.
  15. Haas J, Balcazor H,Caulfeild L. Variation in early neonatal mortality for different types of fetal growth retardation. Am J Phys.Anthropol.73:467-473,1987.
  16. Hoffman H, Bakketeig L. Heterogeneity of intrauterine growth retardation and recurrence risks. Semin Perinatal8:15-24,1984.
  17. Robert M. Patterson et al,Neonatal morphometrics and perinatal outcome: who is growth retarded? Am J Obstet Gynecal September 1987.
  18. Battaglia FC, Lubchenco LO,A practical classification of newborn infants by weight and gestational age, J. Pediatr 71:159-163,1967.
  19. Williams RL, Creasy RK, Cunningham GC, Hawes WE, Morris FD,Fetal growth and perinatal viability in California.Obstet gynecal 59:624-631,1982.
  20. Lubchenco, L.O.H.BARD: Incidence of hypoglycaemia in newborn infants classified by birth weight and gestational age. Pediatrics 47,831:1971.
  21. Sinclair, J.C. Heat production and thermoregulation in the small for date infant. Pediat. Clin N.Amer;17:147,1970.
  22. N. Ezenwa, V.C. Ezeaka.Is canscore a good indicator of fetal malnutrition in preterm newborn.Alex J Med 2017.
  23. Almarzoki JM, Rana DJ. Comparative study between clinical assessment of nutritional status score(CAN Score) and anthropometry in the assessment of fetal malnutrition. Int Res J Med Sci.2015,3(7):8-12.
  24. Kamath MK, Raoss, Shenoy RD. Assessment of fetal malnutrition by body mass index and intrauterine growth curves: a comparative study. Int J Contemp Pediatr.10 may 2016.
  25. Adebami OJ, Oyedeji GA, Owa. JA, Oyelami OA. Maternal factors in the etiology of fetal malnutrition in Nigeria.P ediatr Int.49:150-155,2007.
  26. Jarai I.J.Mestyan K Schultz A, Laxar M, Halasz I Krasy. Body size and neonatal hypoglysemia in intrauterine growth retardation. Early Hum Dev 1:25-38,1977.s
  27. Mehta S, Tendon A, Dua T, Kumari S, Singh SK. Clinical assessment of nutritional status at birth,Indian Pediatr. 35:423-428,1998.
  28. Deodhar J, Jarad R. Study of the prevalence of and high risk factors in the etiology of fetal malnutrition in Nigeria. Pediatr Int 49:150-155,2007.
  29. Preeti Waghmare et al: Assessment of fetal malnutrition by CAN Score.Vol9,Jan2012.
  30. Leeladhar et al. Detertion an fetal malnutrition by CAN Score at birth and its comparison with other methods in determining intrauterine growth. Pediatric infection disease Conference 2010.
  31. Ayse A, Korknaz.Ozlem O Teksam,Murat M, Yurdakok, Sule S Yigit and Gulsevin G. Tekinalp Turk J.Pediatr 53(3);261-8,2011.

Corresponding Author

Dr Bapu Yelam M.D

Assistant Professor, Dept of Paediatrics, Govt Medical College, Nagpur, Maharashtra, India 440003